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双侧下鼻甲息肉样变性酷似鼻内肿瘤:一例报告

Bilateral Polypoid Degeneration of the Inferior Turbinates Mimicking Intranasal Neoplasia: A Case Report.

作者信息

Natsiopoulou Ourania, Riga Dimitra, Giotakis Evangelos I, Giotakis Aris I

机构信息

First Department of Otorhinolaryngology, Hippocration General Hospital of Athens, Medical University of Athens, National and Kapodistrian University of Athens, Athens, GRC.

Department of Pathology, Hippocration General Hospital of Athens, Athens, GRC.

出版信息

Cureus. 2025 Aug 10;17(8):e89739. doi: 10.7759/cureus.89739. eCollection 2025 Aug.

Abstract

Lesions of the inferior turbinate are exceedingly rare, with one retrospective series identifying only 34 cases over 14 years. Of those, approximately 68 % were benign (predominantly hemangiomas), and about 32 % were malignant (most commonly non-Hodgkin's lymphoma). Data on polypoid degeneration of the inferior turbinate are limited, particularly regarding histopathologic features and treatment outcomes. This case report aims to contribute to the existing literature by providing detailed clinical, radiologic, and histologic findings, as well as therapeutic considerations for this rare entity. We report the case of a 43-year-old man from Africa (Democratic Republic of the Congo) presenting with a three-month history of severe nasal obstruction, mouth breathing, and intermittent bilateral epistaxis. Physical examination revealed large, soft, pinkish polypoid masses obstructing both nasal cavities. Imaging studies showed bilateral paraseptal tumors without paranasal sinus involvement. Endoscopic exploration revealed that the tumors originated from the medial mucosal surfaces of the inferior turbinates. The masses were excised with monopolar cautery along with a small part of the normal mucosa of the rest of the inferior turbinates. Histopathological examination revealed polypoid degeneration of fibrous tissue with inflammatory infiltration, edema, seromucous glands, and congested blood vessels. Postoperatively, the patient received antibiotics, nasal irrigation, and nasal ointment. The patient reported substantial improvement in nasal breathing one month later. Nasal cavities were patent without crusting. Polypoid degeneration of the inferior turbinate, although very rare, should be included in the differential diagnosis of inferior turbinate pathology.

摘要

下鼻甲病变极为罕见,一项回顾性研究系列在14年中仅发现34例。其中,约68%为良性(主要是血管瘤),约32%为恶性(最常见的是非霍奇金淋巴瘤)。关于下鼻甲息肉样变性的数据有限,尤其是在组织病理学特征和治疗结果方面。本病例报告旨在通过提供详细的临床、放射学和组织学发现以及针对这种罕见病症的治疗考虑因素,为现有文献做出贡献。我们报告一例来自非洲(刚果民主共和国)的43岁男性病例,其有三个月严重鼻塞、张口呼吸和间歇性双侧鼻出血的病史。体格检查发现大的、柔软的、粉红色息肉样肿物阻塞双侧鼻腔。影像学研究显示双侧鼻中隔旁肿瘤,未累及鼻窦。内镜检查发现肿瘤起源于下鼻甲内侧黏膜表面。使用单极电灼切除肿物以及下鼻甲其余部分的一小部分正常黏膜。组织病理学检查显示纤维组织息肉样变性,伴有炎性浸润、水肿、浆液黏液腺和充血血管。术后,患者接受了抗生素、鼻腔冲洗和鼻用软膏治疗。患者在一个月后报告鼻腔呼吸有显著改善。鼻腔通畅,无结痂。下鼻甲息肉样变性虽然非常罕见,但应纳入下鼻甲病变的鉴别诊断中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c80/12419678/a5d543c0694b/cureus-0017-00000089739-i01.jpg

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