Liu Yiting, Liu Lilong, Yao Zhipeng, Hou Yaxin, Liu Zhenghao, Li Yang, Ding Yuhong, Shi Pengjie, Liu Zheng, Chen Ke
Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Institute of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Bladder (San Franc). 2025 Jun 5;12(3):e21200050. doi: 10.14440/bladder.2025.0004. eCollection 2025.
Bladder cancer (BCa) represents a common malignancy of the urinary system across the globe and poses significant treatment challenges.
This review comprehensively examined the application of laser technology in the treatment of BCa, including thulium (Tm) lasers (e.g., Tm-doped yttrium aluminium garnet [YAG]), GreenLight lasers (e.g., potassium titanyl phosphate-doped YAG and lead aluminum borate-doped YAG), holmium lasers (e.g., Ho-doped YAG), Tm fiber laser (TFL), and diode lasers. Studies have demonstrated that laser technology effectively improves tumor resection quality, reduces intraoperative bleeding, shortens recovery time, and lowers recurrence rates. Among these, Ho-doped YAG and Tm-doped YAG lasers have been shown to reduce tissue damage and enhance resection precision, while the TFL has attracted attention for its efficient tissue cutting and minimal thermal damage. GreenLight lasers offer advantages in preserving surrounding healthy tissues and demonstrate potential for use in outpatient settings. Diode lasers, known for their high-energy efficiency, contribute to improved overall treatment efficacy. This article further explored the benefits, drawbacks, and prospective uses of each laser technology in BCa treatment.
This article thoroughly reviewed the applications of various laser technologies in BCa treatment, highlight their benefits and limitations, and assess their potential roles in future clinical practice.
膀胱癌(BCa)是全球泌尿系统常见的恶性肿瘤,带来了重大的治疗挑战。
本综述全面研究了激光技术在膀胱癌治疗中的应用,包括铥(Tm)激光(如掺铥钇铝石榴石[YAG])、绿激光(如掺钛酸钾钇铝石榴石和掺硼酸铅铝钇铝石榴石)、钬激光(如掺钬钇铝石榴石)、Tm光纤激光(TFL)和二极管激光。研究表明,激光技术能有效提高肿瘤切除质量,减少术中出血,缩短恢复时间,并降低复发率。其中,掺钬钇铝石榴石和掺铥钇铝石榴石激光已被证明可减少组织损伤并提高切除精度,而Tm光纤激光因其高效的组织切割和最小的热损伤而受到关注。绿激光在保留周围健康组织方面具有优势,并显示出在门诊环境中使用的潜力。二极管激光以其高能效著称,有助于提高整体治疗效果。本文进一步探讨了每种激光技术在膀胱癌治疗中的益处、缺点和潜在用途。
本文全面回顾了各种激光技术在膀胱癌治疗中的应用,突出了它们的优点和局限性,并评估了它们在未来临床实践中的潜在作用。