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男性复发性浆细胞性乳腺炎的手术治疗:一例报告

Surgical Management of Recurrent Plasma Cell Mastitis in a Male Patient: A Case Report.

作者信息

Yang Ting, Luo Haijiao, Zhou Jing, Duan Zhongxu, Jing Jingfeng, Gao Han

机构信息

Department of Breast and Thyroid, Women and Children's Hospital of Chongqing Medical University: Chongqing Health Center for Women and Children, Chongqing, People's Republic of China.

School of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, 15200, Malaysia.

出版信息

Int Med Case Rep J. 2025 Sep 4;18:1147-1152. doi: 10.2147/IMCRJ.S534479. eCollection 2025.

DOI:10.2147/IMCRJ.S534479
PMID:40933585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12417701/
Abstract

INTRODUCTION

Plasma Cell Mastitis (PCM) is a rare, chronic inflammatory breast disorder that primarily affects females, although there are occasional reports in males. This case report details an instance of PCM in a male patient, underscoring the diagnostic and therapeutic complexities associated with this condition.

PATIENT CONCERNS

The male patient presented with a palpable parapapillary mass, erythema, and localized breast pain.

DIAGNOSES

Radiological and histopathological assessments confirmed the diagnosis of PCM.

INTERVENTIONS

Initial management included conservative pharmacological therapy, which was ineffective. Subsequently, the patient underwent a minimally invasive surgical intervention to address the breast lesion. However, 10 months post-surgery, a recurrence necessitated a total subcutaneous mastectomy.

OUTCOMES

Despite surgical interventions, the recurrence of PCM highlights the challenges in managing this condition. Complete resolution was achieved following the total subcutaneous mastectomy.

CONCLUSION

This case underscores the importance of recognizing and addressing PCM in male patients. It highlights the absence of a standardized clinical treatment protocol and emphasizes the necessity for personalized management approaches, especially in recurrent cases.

摘要

引言

浆细胞性乳腺炎(PCM)是一种罕见的慢性炎症性乳腺疾病,主要影响女性,不过也有男性发病的偶尔报道。本病例报告详细介绍了一名男性患者的浆细胞性乳腺炎病例,强调了与该疾病相关的诊断和治疗复杂性。

患者情况

该男性患者出现可触及的乳头旁肿块、红斑和局部乳房疼痛。

诊断

放射学和组织病理学评估确诊为浆细胞性乳腺炎。

干预措施

初始治疗包括保守药物治疗,但无效。随后,患者接受了微创外科手术以处理乳腺病变。然而,术后10个月复发,需要进行全皮下乳房切除术。

结果

尽管进行了手术干预,但浆细胞性乳腺炎的复发凸显了治疗该疾病的挑战。全皮下乳房切除术后实现了完全缓解。

结论

本病例强调了认识和治疗男性患者浆细胞性乳腺炎的重要性。它凸显了缺乏标准化临床治疗方案的情况,并强调了个性化管理方法的必要性,尤其是在复发病例中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/8d7583b5939f/IMCRJ-18-1147-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/0bad5ef97a96/IMCRJ-18-1147-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/2e4091da3698/IMCRJ-18-1147-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/2ee7f10791aa/IMCRJ-18-1147-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/816a8aae6158/IMCRJ-18-1147-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/7e0932d00fd5/IMCRJ-18-1147-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/8d7583b5939f/IMCRJ-18-1147-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/0bad5ef97a96/IMCRJ-18-1147-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/2e4091da3698/IMCRJ-18-1147-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/2ee7f10791aa/IMCRJ-18-1147-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/816a8aae6158/IMCRJ-18-1147-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/7e0932d00fd5/IMCRJ-18-1147-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff3/12417701/8d7583b5939f/IMCRJ-18-1147-g0006.jpg

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本文引用的文献

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The role of tissue IgG4 levels in steroid therapy in patients with idiopathic granulomatous mastitis.特发性肉芽肿性乳腺炎患者组织 IgG4 水平在类固醇治疗中的作用。
Clin Exp Med. 2024 Jul 28;24(1):173. doi: 10.1007/s10238-024-01444-7.
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Clinical, histological features, and predictors of relapse in patients with idiopathic granulomatous mastitis.特发性肉芽肿性乳腺炎患者的临床、组织学特征和复发预测因素。
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Identification of periductal mastitis and granulomatous lobular mastitis: a literature review.
导管周围乳腺炎和肉芽肿性小叶性乳腺炎的识别:文献综述
Ann Transl Med. 2023 Feb 15;11(3):158. doi: 10.21037/atm-22-6473. Epub 2023 Feb 3.
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Current Understanding and Management of Plasma Cell Mastitis: Can We Benefit from What We Know?浆细胞性乳腺炎的当前认识与管理:我们能从已知中获益吗?
Breast Care (Basel). 2022 Jun;17(3):321-329. doi: 10.1159/000517572. Epub 2021 Oct 6.
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