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A case of cutaneous angiosarcoma with intradermal metastases responding to PD-1 inhibition-based immunotherapy.

作者信息

Danesh Kayla, Hu Jenny C, Kokot Niels, Goldstein Zachary, DeClerck Brittney, Beutler Bryce, Jadvar Hossein, Butcher Katherine, In Gino K

机构信息

Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, California.

Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, California.

出版信息

JAAD Case Rep. 2025 Jul 9;64:67-70. doi: 10.1016/j.jdcr.2025.05.046. eCollection 2025 Oct.

DOI:10.1016/j.jdcr.2025.05.046
PMID:40933637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12418878/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/fe91d43fb30c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/52ac73dff94b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/926a8ff63166/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/32d57f833c50/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/fe91d43fb30c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/52ac73dff94b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/926a8ff63166/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/32d57f833c50/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abd/12418878/fe91d43fb30c/gr4.jpg

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本文引用的文献

1
Recurrent, Tumor Mutation Burden-High, Cutaneous Angiosarcoma of the Scalp Treated with Pembrolizumab.使用帕博利珠单抗治疗的复发性、肿瘤突变负荷高的头皮皮肤血管肉瘤
Case Rep Oncol. 2023 Nov 28;16(1):1490-1493. doi: 10.1159/000534657. eCollection 2023 Jan-Dec.
2
Patterns of pseudoprogression across different cancer entities treated with immune checkpoint inhibitors.不同实体瘤接受免疫检查点抑制剂治疗后的假性进展模式。
Cancer Imaging. 2023 Jun 8;23(1):58. doi: 10.1186/s40644-023-00580-9.
3
Dramatic Response of a PD-L1-Positive Advanced Angiosarcoma of the Scalp to Pembrolizumab.
头皮PD-L1阳性晚期血管肉瘤对帕博利珠单抗的显著反应
JCO Precis Oncol. 2018 Nov;2:1-7. doi: 10.1200/PO.17.00107.
4
Is PD-L1 a consistent biomarker for anti-PD-1 therapy? The model of balstilimab in a virally-driven tumor.程序性死亡配体1(PD-L1)是抗程序性死亡蛋白1(PD-1)治疗的一致性生物标志物吗?Balstilimab在病毒驱动肿瘤中的模型。
Oncogene. 2021 Feb;40(8):1393-1395. doi: 10.1038/s41388-020-01611-6. Epub 2021 Jan 26.
5
Positron Emission Tomography-Based Response to Target and Immunotherapies in Oncology.基于正电子发射断层扫描的肿瘤靶向和免疫治疗反应。
Medicina (Kaunas). 2020 Jul 24;56(8):373. doi: 10.3390/medicina56080373.
6
The potential mechanism, recognition and clinical significance of tumor pseudoprogression after immunotherapy.免疫治疗后肿瘤假性进展的潜在机制、识别及临床意义
Cancer Biol Med. 2019 Nov;16(4):655-670. doi: 10.20892/j.issn.2095-3941.2019.0144.
7
Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.免疫检查点抑制剂治疗的血管肉瘤患者:来自单一机构的七例患者的病例系列。
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Tumor mutational load predicts survival after immunotherapy across multiple cancer types.肿瘤突变负荷可预测多种癌症类型免疫治疗后的生存情况。
Nat Genet. 2019 Feb;51(2):202-206. doi: 10.1038/s41588-018-0312-8. Epub 2019 Jan 14.
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