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日本姑息治疗团队中针对癌症患者的针灸治疗:一项前瞻性病例系列研究。

Acupuncture for patients with Cancer in a Japanese palliative care team: A prospective case series study.

作者信息

Masuyama Shoko, Yamashita Hitoshi, Amino Tamami, Kawamoto Ryouko, Tsuji Ryota, Nakanishi Hiromoto, Yoshida Hiroshi

机构信息

Graduate School of Health Sciences, Morinomiya University of Medical Sciences, Osaka, Japan.

Department of Acupuncture, Morinomiya University of Medical Sciences, Osaka, Japan.

出版信息

Integr Med Res. 2026 Mar;15(1):101212. doi: 10.1016/j.imr.2025.101212. Epub 2025 Aug 5.

Abstract

BACKGROUND

The joint guidelines of the Society for Integrative Oncology and the American Society of Clinical Oncology recommend acupuncture for pain symptoms in some patients with cancer. This study assessed whether adding acupuncture to usual palliative care alleviates the subjective symptoms of hospitalized patients with cancer in Japan, at least in the short term.

METHODS

Between 2015 and 2019, we conducted a prospective case series study at a regional core hospital in Osaka. Acupuncture was included in the usual care of patients with cancer. The primary outcome was immediate changes in each patient's subjective symptoms measured by a 10 cm visual analog scale (VAS). A 20 % reduction in VAS was set as the minimal clinically important difference (MCID).

RESULTS

A total of 83 cancer patients (mean age: 66.1) were treated with acupuncture. A significant reduction was observed in the VAS scores for pain, edema, nausea, neck/shoulder/back stiffness, and breathlessness during at least one treatment session. The percentage of patients that improved beyond the MCID was as follows: 67 % for pain, 75 % for edema, 60 % for paresthesia, 80 % for nausea, 88 % for stiffness, 38 % for malaise, and 83 % for breathlessness, based on the maximum improvement recorded per session.

CONCLUSION

Japanese-style acupuncture, with relatively finer needles and gentler stimulation, has shown promise as a palliative treatment for patients with cancer, potentially offering temporary relief from pain, edema, nausea, stiffness, and breathlessness. Based on our findings, a pragmatic randomized controlled trial with an appropriate control group is recommended.

摘要

背景

综合肿瘤学会和美国临床肿瘤学会的联合指南建议,对部分癌症患者的疼痛症状采用针灸治疗。本研究评估了在日本,在常规姑息治疗基础上加用针灸是否能缓解癌症住院患者的主观症状,至少在短期内是否有效。

方法

2015年至2019年期间,我们在大阪的一家地区核心医院进行了一项前瞻性病例系列研究。针灸被纳入癌症患者的常规护理中。主要结局是通过10厘米视觉模拟量表(VAS)测量的每位患者主观症状的即时变化。将VAS评分降低20%设定为最小临床重要差异(MCID)。

结果

共有83例癌症患者(平均年龄:66.1岁)接受了针灸治疗。在至少一个治疗疗程中,观察到疼痛、水肿、恶心、颈/肩/背僵硬和呼吸急促的VAS评分显著降低。根据每个疗程记录的最大改善情况,改善超过MCID的患者百分比分别为:疼痛67%、水肿75%、感觉异常60%、恶心80%、僵硬88%、不适38%、呼吸急促83%。

结论

日式针灸使用相对较细的针和较温和的刺激,已显示出有望成为癌症患者的姑息治疗方法,可能会暂时缓解疼痛、水肿、恶心、僵硬和呼吸急促。基于我们的研究结果,建议进行一项有适当对照组的实用随机对照试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f22/12419068/735e9baedc45/gr1.jpg

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