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一位年轻女性患有局部支气管内侵犯的肺黏液表皮样癌:单孔胸腔镜辅助下袖状肺叶切除术成功治疗的病例报告

Pulmonary mucoepidermoid carcinoma with local intrabronchial invasion in a young lady: A case report of successful management via uniportal VATS sleeve lobectomy.

作者信息

Essa Rawand Abdulrahman, Sulaiman Diyar Saddam, HamadAmen Kalthuma Saleh, Abdulla Saman Salaheldeen, Salih Rebaz Hamza, Sulaiman Luqman Rahman

机构信息

University of Kurdistan Hawler, School of Medicine, Erbil, Kurdistan region, Iraq; Rizgary Teaching Hospital, Erbil, Kurdistan region, Iraq.

Rizgary Teaching Hospital, Erbil, Kurdistan region, Iraq.

出版信息

Int J Surg Case Rep. 2025 Oct;135:111895. doi: 10.1016/j.ijscr.2025.111895. Epub 2025 Sep 6.

Abstract

INTRODUCTION AND IMPORTANCE

Mucoepidermoid carcinoma (MEC) is an extremely rare type of lung cancer, accounting for approximately 0.2-0.4 % of all lung cancers. It typically presents as a central airway lesion, with symptoms such as cough, hemoptysis, bronchitis, wheezing, fever, chest pain, and clubbing of the fingers. Histologically similar to tumors in major salivary glands, it mostly arises from small salivary glands that line the tracheobronchial tree.

CASE PRESENTATION

We have reported a rare case of intrabronchial mucoepidermoid carcinoma that extended extra-bronchially in a 25-year-old female presenting with hemoptysis for 10 days associated with mild cough and wheezing. A computerized tomography (CT) scan revealed a 3.5 cm lesion in the right upper bronchus, and fiber optic bronchoscopy confirmed an intrabronchial lesion. We performed right sleeve lobectomy via a novel Uniportal video-assisted thoracoscopic surgery (U-VATS) approach.

DISCUSSION

Since Mucoepidermoid carcinoma (MEC) frequently manifests with vague symptoms, diagnosing it when it spreads from extra-bronchial intrabronchial can be difficult and uncommon. The typical histology of Mucoepidermoid carcinoma (MEC) composed of varying 3 cell types, but the histology of our case was single cell type and it was diagnosed by genetic analysis in another advanced hospital. The effectiveness and safety of Uniportal video-assisted thoracoscopic surgery (UVATS) have been acknowledged globally. Shorter surgical times, less pain, and a decreased requirement for extensive chest tube drainage are all linked to this technique.

CONCLUSION

This case illustrates how a young woman's intrabronchial mucoepidermoid carcinoma was successfully treated with a sleeve lobectomy performed via Uniportal video-assisted thoracoscopic surgery (VATS).

摘要

引言与重要性

黏液表皮样癌(MEC)是一种极为罕见的肺癌类型,约占所有肺癌的0.2 - 0.4%。它通常表现为中央气道病变,症状包括咳嗽、咯血、支气管炎、喘息、发热、胸痛和杵状指。在组织学上与大唾液腺肿瘤相似,它大多起源于气管支气管树的小唾液腺。

病例介绍

我们报告了一例罕见的支气管内黏液表皮样癌病例,该病例在一名25岁咯血10天且伴有轻度咳嗽和喘息的女性中向支气管外扩展。计算机断层扫描(CT)显示右上支气管有一个3.5厘米的病变,纤维支气管镜检查证实为支气管内病变。我们通过一种新型单孔电视辅助胸腔镜手术(U-VATS)方法进行了右袖状肺叶切除术。

讨论

由于黏液表皮样癌(MEC)常表现出模糊的症状,当它从支气管外扩散到支气管内时,诊断可能困难且不常见。黏液表皮样癌(MEC)的典型组织学由三种不同的细胞类型组成,但我们病例的组织学为单一细胞类型,且在另一家高级医院通过基因分析得以诊断。单孔电视辅助胸腔镜手术(UVATS)的有效性和安全性已得到全球认可。手术时间缩短、疼痛减轻以及对广泛胸腔闭式引流的需求减少均与该技术相关。

结论

本病例说明了一名年轻女性的支气管内黏液表皮样癌如何通过单孔电视辅助胸腔镜手术(VATS)进行的袖状肺叶切除术成功治疗。

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