Lee Inji, Kang Minji, Choi Ji Hye, Lim Hyunjung, Chon Suk
Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea.
Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Korea.
Diabetes Metab J. 2025 Sep;49(5):951-963. doi: 10.4093/dmj.2025.0675. Epub 2025 Sep 1.
As the prevalence of type 2 diabetes mellitus continues to rise, the development of effective and sustainable prevention strategies has become a critical public health priority. Evidence from large-scale randomized controlled trials has established that lifestyle modification (LSM) programs can substantially reduce the risk of diabetes in high-risk individuals. However, routine implementation is limited by high intensity, costs, and resource requirements. We summarize major prevention trials and their effectiveness, feasibility, and limitations. Building on these insights, we introduce the Korean Diabetes Prevention Study (KDPS) as a contextually tailored model for the Korean healthcare system. The KDPS-LSM program was designed to integrate cultural and clinical relevance with practical applicability, consisting of a 6-month intensive phase of structured nutrition and lifestyle education followed by a maintenance phase to support long-term adherence. To promote sustainable change, the program incorporates the '10 habit' lifestyle messages, grounded in the transtheoretical model of behavior change, which are designed for easy implementation in daily life. This review underscores the importance of developing culturally appropriate LSM programs that balance effectiveness with feasibility, and suggests that the KDPS-LSM model could serve as a useful foundation for establishing practical diabetes prevention strategies within national healthcare systems.
随着2型糖尿病患病率持续上升，制定有效且可持续的预防策略已成为公共卫生的关键优先事项。大规模随机对照试验的证据表明，生活方式改变（LSM）项目可大幅降低高危个体患糖尿病的风险。然而，常规实施受到高强度、成本和资源需求的限制。我们总结了主要的预防试验及其有效性、可行性和局限性。基于这些见解，我们介绍韩国糖尿病预防研究（KDPS），它是针对韩国医疗体系量身定制的模式。KDPS-LSM项目旨在将文化和临床相关性与实际适用性相结合，包括为期6个月的结构化营养和生活方式强化教育阶段，随后是支持长期坚持的维持阶段。为促进可持续改变，该项目纳入了基于行为改变跨理论模型的“10个习惯”生活方式信息，这些信息旨在便于在日常生活中实施。本综述强调了制定在有效性与可行性之间取得平衡的文化适宜性LSM项目的重要性，并表明KDPS-LSM模式可为在国家医疗体系内制定切实可行的糖尿病预防策略提供有益基础。
