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一种新型的保留关节手术方法治疗儿童桡骨远端骨巨细胞瘤:病例报告及文献综述

A Novel, Joint Sparing Surgical Approach to the Management of Giant Cell Tumor of the Distal Radius in a Pediatric Patient: A Case Report and Comprehensive Literature Review.

作者信息

Lalchandani Tushar, Das Lakshmana, Sharma Pankaj, Goyal Tarun, Barwar Nilesh

机构信息

Department of Orthopaedics, All India Institute of Medical Sciences, Bathinda, Punjab, India.

出版信息

J Orthop Case Rep. 2025 Sep;15(9):95-100. doi: 10.13107/jocr.2025.v15.i09.6028.

DOI:10.13107/jocr.2025.v15.i09.6028
PMID:40936819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12422635/
Abstract

INTRODUCTION

Giant cell tumor (GCT) of bone is a rare, locally aggressive neoplasm predominantly affecting skeletally mature individuals, with infrequent, uncommon occurrence in the pediatric population.

CASE REPORT

This case report describes a young skeletally immature female presenting with a Campanacci grade 3 GCT of the distal radius, characterized an osteolytic lesion sparing the epiphysis. Following biopsy confirmation, the patient underwent wide local excision of the tumor with ulnar translocation, fixed using a distal radius locking plate to preserve joint integrity. Post-operative rehabilitation included physiotherapy to restore wrist mobility and grip strength.

RESULTS

At 2 years post-surgery, the patient demonstrated no re-occurrence of tumor and satisfactory functional outcomes, including 90° dorsiflexion, 35° palmar flexion, 60° pronosupination, and 68% grip strength compared to the contralateral side.

CONCLUSION

This report highlights an innovative surgical approach that preserves joint functionality in pediatric GCT cases, emphasizing the importance of anatomical reconstruction and long-term functional restoration.

摘要

引言

骨巨细胞瘤(GCT)是一种罕见的、具有局部侵袭性的肿瘤,主要影响骨骼成熟的个体,在儿科人群中发生率很低且不常见。

病例报告

本病例报告描述了一名骨骼未成熟的年轻女性,患有桡骨远端的坎帕纳奇3级骨巨细胞瘤,其特征为一个不累及骨骺的溶骨性病变。活检确诊后,患者接受了肿瘤广泛局部切除并尺骨移位,使用桡骨远端锁定钢板固定以保持关节完整性。术后康复包括物理治疗以恢复腕关节活动度和握力。

结果

术后2年,患者未出现肿瘤复发,功能结果令人满意,包括背屈90°、掌屈35°、旋前旋后60°,与对侧相比握力为68%。

结论

本报告强调了一种在儿科骨巨细胞瘤病例中保留关节功能的创新手术方法,强调了解剖重建和长期功能恢复的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/fd1a5c597a85/JOCR-15-95-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/22308b0a1cd4/JOCR-15-95-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/cbe94185c334/JOCR-15-95-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/8d2971f95aef/JOCR-15-95-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/98ee944f3c87/JOCR-15-95-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/fd1a5c597a85/JOCR-15-95-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/22308b0a1cd4/JOCR-15-95-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/cbe94185c334/JOCR-15-95-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/8d2971f95aef/JOCR-15-95-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/98ee944f3c87/JOCR-15-95-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f15/12422635/fd1a5c597a85/JOCR-15-95-g005.jpg

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本文引用的文献

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Giant Cell Tumor of Distal Radius Treated with Wide Local Excision and Reconstruction with Ipsilateral Proximal Fibular Autograft - A Follow-Up.采用同侧近端腓骨自体骨移植进行广泛局部切除及重建治疗桡骨远端骨巨细胞瘤——随访
J Orthop Case Rep. 2025 Jan;15(1):41-45. doi: 10.13107/jocr.2025.v15.i01.5118.
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Aneurysmal Bone Cyst of the Distal Ulna in an Elderly Lady.一位老年女性尺骨远端的动脉瘤样骨囊肿
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Management of giant cell tumors of the distal radius.桡骨远端骨巨细胞瘤的治疗
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Characteristics of Giant Cell Tumor of the Bone in Pediatric Patients: Our 18-Year, Single-Center Experience.儿童骨巨细胞瘤的特征:我们18年的单中心经验
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Giant Cell Tumor with Fracture of the Proximal Radius - Reconstructive Surgery with Radius Allograft.桡骨近端骨折合并骨巨细胞瘤——同种异体桡骨重建手术
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Retrospective Analysis of Giant Cell Tumor Lower End Radius Treated with Excision and Translocation of Ulna.尺骨切除移位治疗桡骨下端骨巨细胞瘤的回顾性分析
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