Takagi Keigo, Sugihara Kazunobu, Iida Mizuki, Murakami Kana, Ida Chisako, Ohtani Hinako, Tanito Masaki
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Cureus. 2025 Sep 10;17(9):e91977. doi: 10.7759/cureus.91977. eCollection 2025 Sep.
This report describes three cases of iris retraction syndrome (IRS) associated with long-standing rhegmatogenous retinal detachment (RRD), all presenting with hypotony, abnormally deep anterior chambers, and ciliary body detachment, often accompanied by dense cataracts and uveitis-like findings that initially obscured the underlying pathology. In each case, anti-inflammatory therapy led to partial resolution of anterior segment abnormalities, subsequently revealing RRD that required pars plana vitrectomy with or without combined cataract surgery. Postoperatively, most cases maintained stable IOP, although one developed secondary ocular hypertension necessitating glaucoma therapy. These cases highlight that IRS can mask its primary cause; careful evaluation for RRD or other causes is warranted when posterior iris bowing is observed in hypotonic eyes, and long-term IOP monitoring remains important even after successful treatment of the underlying pathology.
本报告描述了3例与长期孔源性视网膜脱离（RRD）相关的虹膜后缩综合征（IRS），所有病例均表现为低眼压、前房异常加深和睫状体脱离，常伴有致密白内障和葡萄膜炎样表现，这些表现最初掩盖了潜在的病理情况。在每例病例中，抗炎治疗使前段异常部分缓解，随后发现RRD，需要进行玻璃体切割术联合或不联合白内障手术。术后，大多数病例眼压保持稳定，尽管有1例发生继发性高眼压，需要进行青光眼治疗。这些病例表明，IRS可掩盖其主要病因；当在低眼压眼中观察到虹膜后凸时，有必要仔细评估RRD或其他病因，即使在潜在病理情况成功治疗后，长期眼压监测仍然很重要。
