Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Shimane.
Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, Japan.
J Glaucoma. 2020 Sep;29(9):807-812. doi: 10.1097/IJG.0000000000001560.
PRéCIS:: Creation of a cyclodialysis cleft can be a mechanism of ciliochoroidal detachment (CCD) and associated persistent hypotony after microhook ab interno trabeculotomy (μLOT).
To report persistent hypotony after μLOT, a minimally invasive glaucoma surgery (MIGS).
This observational case series included 4 consecutive cases (3 men, 1 woman; mean age, 48.8±15.1 y) of persistent hypotony that developed after μLOT between May 2015 and March 2018. The patients' data and surgical results were obtained from the medical charts.
All patients had open-angle glaucoma (2 juvenile, 1 primary, and 1 pigmentary) and were myopic (axial lengths, >24 mm). Two patients had undergone previous refractive surgery. μLOT alone was performed in 2 cases and combined with cataract surgery in 2 cases. In all cases, hypotony below 5 mm Hg was recorded 1 day postoperatively and sustained. In all cases, ultrasound biomicroscopy showed an annular CCD; communication between the anterior chamber and suprachoroidal space was detected in 3 of 4 cases. The hypotony resolved in 3 of the 4 cases from 2 to 8 months postoperatively, that is, spontaneously in 2 cases (cases 1 and 4) and after sulfur hexafluoride gas injection into the anterior chamber in 1 case (case 2). CCD resolution accompanied remarkedly high intraocular pressure, which required filtration surgeries. The incidence of persistent hypotony was 0.7% (4/547 eyes).
After MIGS, persistent hypotony because of CCD rarely occurs. Increased uveoscleral outflow because of LOT or creation of a cyclodialysis cleft by traction of the pectinate ligament can be a mechanism of CCD development. Young age and myopia can be risks for cyclodialysis cleft formation and hypotony maculopathy after MIGS.
报告微创青光眼手术(MIGS)后发生的 μLOT 后持续性低眼压。
本观察性病例系列研究纳入了 2015 年 5 月至 2018 年 3 月期间接受 μLOT 后发生持续性低眼压的 4 例连续病例(3 例男性,1 例女性;平均年龄 48.8±15.1 岁)。从病历中获取患者数据和手术结果。
所有患者均患有开角型青光眼(2 例青少年型,1 例原发性,1 例色素性)和近视(眼轴长度>24mm)。2 例患者曾接受过屈光手术。2 例单独行 μLOT,2 例联合白内障手术。所有病例术后第 1 天均记录到眼压<5mmHg,且持续低眼压。所有病例超声生物显微镜均显示环形睫状体脱离;4 例中有 3 例检测到前房和脉络膜上腔之间存在交通。4 例中有 3 例的低眼压在术后 2 至 8 个月内自行缓解(2 例病例 1 和病例 4 自发缓解,1 例病例 2 在前房注入六氟化硫气体后缓解)。睫状体脱离缓解后眼内压显著升高,需要行滤过性手术。持续性低眼压的发生率为 0.7%(4/547 眼)。
MIGS 后很少因睫状体脱离导致持续性低眼压。LOT 导致的葡萄膜巩膜外流增加或牵引梳状韧带导致的睫状体分离可能是睫状体脱离发展的机制。年轻和近视可能是 MIGS 后形成睫状体分离和低眼压性黄斑病变的危险因素。