Shaker Anisa, Soffer Edy
Swallowing and Esophageal Disorders Center, Division of Gastrointestinal and Liver Diseases, Department of Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90089, USA.
Mini Invasive Surg. 2025;9. doi: 10.20517/2574-1225.2024.105. Epub 2025 Aug 26.
Obesity remains a global public health burden. The most common surgical approach for this condition worldwide is laparoscopic sleeve gastrectomy (LSG). Although it is highly effective at achieving both short- and long-term weight loss, comparable to outcomes demonstrated by Roux-en-Y gastric bypass, there are growing concerns about the development or worsening of another prevalent and morbid condition, gastroesophageal reflux disease (GERD), following sleeve gastrectomy (SG). In this narrative review, we summarize current concerns related to GERD in the context of SG. We review the pathophysiologic mechanisms that predispose the SG anatomy to GERD, focus on the prevalence of and worsening GERD and its associated complications, Barrett's esophagus, review expert recommendations for GERD evaluation pre- and post-surgery, and discuss therapeutic options for those with severe GERD following SG.
肥胖仍然是一个全球性的公共卫生负担。在全球范围内，针对这种情况最常见的手术方法是腹腔镜袖状胃切除术（LSG）。尽管它在实现短期和长期体重减轻方面非常有效，与Roux-en-Y胃旁路手术的效果相当，但人们越来越担心在袖状胃切除术（SG）后，另一种普遍且严重的疾病——胃食管反流病（GERD）会出现或恶化。在这篇叙述性综述中，我们总结了在SG背景下与GERD相关的当前关注点。我们回顾了使SG解剖结构易患GERD的病理生理机制，关注GERD的患病率和病情恶化情况及其相关并发症——巴雷特食管，回顾了术前和术后GERD评估的专家建议，并讨论了SG后患有严重GERD者的治疗选择。
