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扩张型心肌病中可移动左心室血栓的急诊切除:多器官栓塞及术后室性心动过速一例

The Emergency Resection of a Mobile Left Ventricular Thrombus in Dilated Cardiomyopathy: A Case of Multiorgan Embolism and Postoperative Ventricular Tachycardia.

作者信息

Ota Soichiro, Hayashi Yuki, Kamata Keita, Eguchi Naoki, Tanaka Masashi

机构信息

Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, JPN.

出版信息

Cureus. 2025 Aug 10;17(8):e89756. doi: 10.7759/cureus.89756. eCollection 2025 Aug.

DOI:10.7759/cureus.89756
PMID:40937201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12420944/
Abstract

Dilated cardiomyopathy (DCM) is characterized by marked left ventricular (LV) dilation and systolic dysfunction, which predispose patients with DCM to LV thrombus (LVT) formation and potentially fatal multiorgan embolism. We report the case of a 52-year-old male with severe DCM (ejection fraction (EF), 14%; LV diameter, 89 mm) who developed a large, mobile LVT (40 × 30 mm) that caused embolic events in the lungs, kidneys, spleen, superior mesenteric artery, and posterior cerebral cortex. Since anticoagulation therapy was deemed insufficient to control the embolic source, emergency surgical thrombectomy was performed via an apical LV incision. Although the patient's condition initially stabilized, he developed ventricular tachycardia and torsades de pointes on postoperative day (POD) nine, which led to cardiac arrest. He was successfully resuscitated but required intensive antiarrhythmic therapy and circulatory support. The patient was discharged on POD 41 with an implantable cardioverter-defibrillator. This report illustrates that surgical removal of a large, mobile LVT is effective in controlling embolic events; however, an LV incision may induce postoperative life-threatening ventricular arrhythmias due to myocardial scarring and electrical heterogeneity. Rigorous perioperative monitoring and comprehensive arrhythmia management are essential when surgical thrombectomy is considered for LVT related to DCM.

摘要

扩张型心肌病(DCM)的特征是左心室(LV)明显扩张和收缩功能障碍,这使DCM患者易形成左心室血栓(LVT),并可能引发致命的多器官栓塞。我们报告了一例52岁男性重度DCM患者(射血分数(EF)为14%;左心室直径为89 mm),该患者形成了一个大的、可移动的LVT(40×30 mm),导致肺部、肾脏、脾脏、肠系膜上动脉和大脑后皮质发生栓塞事件。由于抗凝治疗被认为不足以控制栓子来源,遂通过左心室心尖切口进行了急诊手术取栓。尽管患者病情最初稳定,但在术后第9天出现室性心动过速和尖端扭转型室速,导致心脏骤停。他成功复苏,但需要强化抗心律失常治疗和循环支持。患者于术后第41天植入植入式心脏复律除颤器后出院。本报告表明,手术切除大的、可移动的LVT可有效控制栓塞事件;然而,左心室切口可能因心肌瘢痕形成和电不均一性而诱发术后危及生命的室性心律失常。对于与DCM相关的LVT考虑进行手术取栓时,严格的围手术期监测和全面的心律失常管理至关重要。

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