Rodrigues Alexandra, Torres Lara, Salgueiro Rita, González Isabel, Oliveira Rita S
Department of Pediatrics, Unidade Local de Saude da Guarda, Guarda, PRT.
Cureus. 2025 Aug 10;17(8):e89760. doi: 10.7759/cureus.89760. eCollection 2025 Aug.
Primary amenorrhea is the absence of menses at age 15 with secondary sexual characteristics or at age 13 without any secondary sexual characteristics. Evaluation for primary amenorrhea should also be considered when menarche has not occurred within three years of thelarche, or five years after thelarche if it began before the age of 10. We report a rare case of a 15-year-old adolescent with primary amenorrhea who was diagnosed with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. The diagnosis was established through magnetic resonance imaging. The patient is currently undergoing multidisciplinary follow-up, including psychological support. At present, the use of vaginal dilators or surgical intervention is being considered as the most appropriate therapeutic approach.
原发性闭经是指15岁有第二性征但无月经初潮，或13岁无任何第二性征。如果乳房发育后3年内仍未出现月经初潮，或乳房发育始于10岁之前，那么乳房发育后5年仍未出现月经初潮时，也应考虑对原发性闭经进行评估。我们报告一例罕见的15岁原发性闭经青少年病例，该患者被诊断为 Mayer-Rokitansky-Küster-Hauser（MRKH）综合征。诊断通过磁共振成像确定。患者目前正在接受多学科随访，包括心理支持。目前，使用阴道扩张器或手术干预被认为是最合适的治疗方法。
