Choksi Ankur U, Smani Shayan, Lokeshwar Soum D, Sundaresan Vinaik M, Hayden Christopher S, Segal Daniel A, Kellner Daniel S
Department of Urology, Yale School of Medicine, Yale University, New Haven, Connecticut 06510, United States of America.
J Biol Methods. 2025 Aug 20;12(3):e99010069. doi: 10.14440/jbm.2025.0002. eCollection 2025.
Holmium laser enucleation of the prostate (HoLEP) has emerged as an effective surgical treatment for benign prostatic hyperplasia (BPH). This study evaluated how the adoption of HoLEP in a general urology clinic influenced clinical and procedural volume.
To better understand the practice ramifications of HoLEP adoption, we analyzed the changes to a general urologist's patient demographics and practice patterns after the addition of HoLEP to their surgical repertoire.
We retrospectively reviewed the electronic health records 30 months before and after the introduction of HoLEP to examine changes in a general urologist's patient population. Pearson's Chi-squared test and Student's -test were used for statistical analysis.
A total of 4390 unique patients were seen over a period of 5-years, with 2052 seen before and 2338 after the introduction of HoLEP. The mean distance from patients' residence zip codes to the treatment center remained statistically unchanged (pre-HoLEP: 32.52 ± 152.42 miles, post-HoLEP: 29.65 ± 141.79 miles, =0.9896). Among those who underwent HoLEP, prostate sizes were comparable between patients residing in the same county and those coming from different counties (96.42 ± 3.24 cc vs. 104.52 ± 4.34 cc, =0.141). Surgical volume rose from 355 to 1018 cases with a concordant increase in other BPH-related surgeries, marked by an inflection point at the time of HoLEP's introduction.
There was an increase in clinical and surgical volume to an established general urologist's practice after HoLEP was offered. Most patients continued to be drawn from the initial catchment area, potentially reflecting previously unmet treatment needs for patients with large prostate glands.
钬激光前列腺剜除术(HoLEP)已成为治疗良性前列腺增生(BPH)的一种有效手术方法。本研究评估了在普通泌尿外科诊所采用HoLEP如何影响临床和手术量。
为了更好地理解采用HoLEP对临床实践的影响,我们分析了一名普通泌尿外科医生在其手术方案中增加HoLEP后患者人口统计学特征和临床实践模式的变化。
我们回顾性分析了引入HoLEP前后30个月的电子健康记录,以检查普通泌尿外科医生患者群体的变化。采用Pearson卡方检验和学生t检验进行统计分析。
在5年的时间里,共诊治了4390例不同患者,引入HoLEP前诊治2052例,引入后诊治2338例。患者居住邮编到治疗中心的平均距离在统计学上保持不变(HoLEP前:32.52±152.42英里,HoLEP后:29.65±141.79英里,P=0.9896)。在接受HoLEP治疗的患者中,同一县内居住的患者与来自不同县的患者前列腺大小相当(96.42±3.24立方厘米对104.52±4.34立方厘米,P=0.141)。手术量从355例增加到1018例,其他与BPH相关的手术也相应增加,以引入HoLEP时为转折点。
提供HoLEP后,一名成熟的普通泌尿外科医生的临床和手术量有所增加。大多数患者仍来自最初的服务区域,这可能反映了之前大前列腺患者未得到满足的治疗需求。