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使用不同激光照射角度对牙龈及种植体周围炎症进行激光热消融的数值分析。

Numerical Analysis of Laser Thermal Ablation for Gingival and Peri-Implant Inflammation Using Various Laser Irradiation Angles.

作者信息

Kim Donghyuk, Kim Hyunjung, Kim Hee-Sun

机构信息

Department of Mechanical Engineering, Ajou University, Suwon-si, Gyeonggi-do, Korea.

Department of Dentistry, SMG_SNU Boramae Medical Center, Seoul, Korea.

出版信息

Int J Numer Method Biomed Eng. 2025 Sep;41(9):e70080. doi: 10.1002/cnm.70080.

DOI:10.1002/cnm.70080
PMID:40938571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12429007/
Abstract

Because of tooth decay and loss, many people use dental implants as tooth replacements. However, careless management can trigger an inflammatory reaction to an implant. Recently, various studies have been conducted on the sterilization and purification of implant surfaces using diodes, Er:YAG lasers, and CO lasers. In this study, the therapeutic effect of photothermal therapy, a laser treatment method for peri-implantitis, was analyzed through numerical analysis based on heat-transfer theory. The numerical simulation conditions included laser power values in the range of 0.0-4.0 W, laser irradiation angles ranging from 15° to 40°, and laser irradiation durations of 100-500 s. In addition, the Arrhenius damage integral was used to quantitatively verify the therapeutic effects of the photothermal therapy. An analysis of the results confirmed that the Arrhenius thermal damage ratio and normal tissue Arrhenius thermal damage ratio decreased as the laser irradiation angle increased. However, for the same normal tissue Arrhenius thermal damage ratio, the effective laser intensity increased with the laser angle. Finally, the effectiveness of photothermal therapy for peri-implantitis under various conditions was confirmed. These results are expected to optimize the clinical treatment of peri-implantitis in the future.

摘要

由于龋齿和牙齿缺失,许多人使用牙种植体来替代牙齿。然而,管理不当会引发对种植体的炎症反应。最近,已经开展了各种关于使用二极管、铒:钇铝石榴石激光和二氧化碳激光对种植体表面进行消毒和净化的研究。在本研究中,基于传热理论通过数值分析对光热疗法(一种用于种植体周围炎的激光治疗方法)的治疗效果进行了分析。数值模拟条件包括0.0 - 4.0 W范围内的激光功率值、15°至40°的激光照射角度以及100 - 500 s的激光照射持续时间。此外,使用阿累尼乌斯损伤积分来定量验证光热疗法的治疗效果。结果分析证实,随着激光照射角度增加,阿累尼乌斯热损伤率和正常组织阿累尼乌斯热损伤率降低。然而,对于相同的正常组织阿累尼乌斯热损伤率,有效激光强度随激光角度增加。最后,证实了光热疗法在各种条件下对种植体周围炎的有效性。这些结果有望在未来优化种植体周围炎的临床治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/cb97e401cac4/CNM-41-e70080-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/8361938a3282/CNM-41-e70080-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/1edfc671095c/CNM-41-e70080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/8f6ce0f90034/CNM-41-e70080-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/3bb306a51fa2/CNM-41-e70080-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/cb97e401cac4/CNM-41-e70080-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/8361938a3282/CNM-41-e70080-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/1edfc671095c/CNM-41-e70080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/8f6ce0f90034/CNM-41-e70080-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/3bb306a51fa2/CNM-41-e70080-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cbf/12429007/cb97e401cac4/CNM-41-e70080-g002.jpg

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本文引用的文献

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Analysis of Peri-Implantitis Photothermal Therapy Effect According to Laser Irradiation Location and Angle: A Numerical Approach.基于激光照射位置和角度的种植体周围炎光热疗法效果分析:一种数值方法
Biomedicines. 2024 Sep 1;12(9):1976. doi: 10.3390/biomedicines12091976.
2
Optimization of photothermal therapy conditions through diffusion analysis based on the initial injection radius of AuNPs.基于金纳米颗粒初始注射半径通过扩散分析优化光热治疗条件。
Int J Numer Method Biomed Eng. 2024 Sep;40(9):e3854. doi: 10.1002/cnm.3854. Epub 2024 Jul 25.
3
Numerical study on the three-dimensional temperature distribution according to laser conditions in photothermal therapy of peri-implantitis.
种植体周围炎光热治疗中基于激光条件的三维温度分布数值研究
Int J Implant Dent. 2024 Apr 24;10(1):19. doi: 10.1186/s40729-024-00537-y.
4
Implantation and reimplantation: epidemiology, etiology and pathogenesis over the last 30 years.种植体的植入和再植入:过去 30 年来的流行病学、病因学和发病机制。
Eur Arch Otorhinolaryngol. 2024 Aug;281(8):4095-4102. doi: 10.1007/s00405-024-08568-2. Epub 2024 Mar 20.
5
LASER as a tool for surface modification of dental biomaterials: A review.激光作为牙科生物材料表面改性的工具:综述
Heliyon. 2023 Jun 20;9(6):e17457. doi: 10.1016/j.heliyon.2023.e17457. eCollection 2023 Jun.
6
Peptide-mediated Aqueous Synthesis of NIR-II Emitting Ag S Quantum Dots for Rapid Photocatalytic Bacteria Disinfection.用于快速光催化细菌消毒的近红外二区发射的Ag₂S量子点的肽介导水相合成
Angew Chem Int Ed Engl. 2023 Mar 27;62(14):e202300085. doi: 10.1002/anie.202300085. Epub 2023 Feb 27.
7
Photo/mechanical and physical implant surface decontamination approaches in conjunction with surgical peri-implantitis treatment: A systematic review.光/机械和物理植入物表面去污方法联合手术治疗种植体周围炎:系统评价。
J Clin Periodontol. 2023 Jun;50 Suppl 26:317-335. doi: 10.1111/jcpe.13783. Epub 2023 Feb 26.
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Bioeng Transl Med. 2022 Aug 4;8(1):e10380. doi: 10.1002/btm2.10380. eCollection 2023 Jan.
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Clin Oral Implants Res. 2022 Nov;33(11):1114-1124. doi: 10.1111/clr.13994. Epub 2022 Sep 16.