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基于激光照射位置和角度的种植体周围炎光热疗法效果分析:一种数值方法

Analysis of Peri-Implantitis Photothermal Therapy Effect According to Laser Irradiation Location and Angle: A Numerical Approach.

作者信息

Kim Donghyuk, Kim Hyunjung, Kim Hee-Sun

机构信息

Department of Mechanical Engineering, Ajou University, Suwon-si 16499, Republic of Korea.

Department of Dentistry, SMG SNU Boramae Medical Center, Seoul 07061, Republic of Korea.

出版信息

Biomedicines. 2024 Sep 1;12(9):1976. doi: 10.3390/biomedicines12091976.

DOI:10.3390/biomedicines12091976
PMID:39335490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11428655/
Abstract

In recent years, dental implants have become increasingly popular around the world. However, if the implant is not properly managed, inflammation may occur, and the implant itself may need to be removed. Peri-implantitis is a common inflammation that occurs in dental implants, and various laser treatments have recently been studied to eliminate it. In this study, the situation of removing peri-implantitis using photothermal therapy, one of the various laser treatments, was analyzed theoretically and numerically. The temperature distribution in the tissue for various laser irradiation locations, angles, and power was calculated based on heat transfer theory, and the degree of thermal damage to tissue was analyzed using the Arrhenius damage integral. In addition, the thermally damaged region ratio of inflamed and normal tissue was analyzed using the Arrhenius thermal damage ratio and normal tissue Arrhenius thermal damage ratio to confirm the trend of treatment results for each treatment condition. The results of the study showed that if only the thermal damage to the inflamed tissue is considered, the laser should be angled vertically, and the laser should be applied to the center of the inflamed tissue rather than close to the implant. However, if the thermal damage to the surrounding normal tissue is also considered, it was found that the laser should be applied at 1.0 mm from the right end of the inflamed tissue for maximum effect. This will allow for more accurate clinical treatment of peri-implantitis in the future.

摘要

近年来,牙种植体在全球范围内越来越受欢迎。然而,如果种植体管理不当,可能会发生炎症,甚至可能需要移除种植体本身。种植体周围炎是牙种植体中常见的一种炎症,最近人们对各种激光治疗方法进行了研究,以消除这种炎症。在本研究中,对使用光热疗法(各种激光治疗方法之一)消除种植体周围炎的情况进行了理论和数值分析。基于传热理论计算了不同激光照射位置、角度和功率下组织中的温度分布,并使用阿累尼乌斯损伤积分分析了组织的热损伤程度。此外,利用阿累尼乌斯热损伤率和正常组织阿累尼乌斯热损伤率分析了炎症组织和正常组织的热损伤区域比例,以确定每种治疗条件下的治疗结果趋势。研究结果表明,如果仅考虑对炎症组织的热损伤,激光应垂直照射,且应照射在炎症组织的中心而非靠近种植体的位置。然而,如果也考虑对周围正常组织的热损伤,则发现激光应从炎症组织右端1.0毫米处照射,以达到最大效果。这将为未来更准确地临床治疗种植体周围炎提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/521209e67cca/biomedicines-12-01976-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/a95b4609eca3/biomedicines-12-01976-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/183623bcab70/biomedicines-12-01976-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/9704e1fbb764/biomedicines-12-01976-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/108c2a72270a/biomedicines-12-01976-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/521209e67cca/biomedicines-12-01976-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/a95b4609eca3/biomedicines-12-01976-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/183623bcab70/biomedicines-12-01976-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/9704e1fbb764/biomedicines-12-01976-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/108c2a72270a/biomedicines-12-01976-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5131/11428655/521209e67cca/biomedicines-12-01976-g005.jpg

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Sci Rep. 2023 Jul 26;13(1):12135. doi: 10.1038/s41598-023-39040-6.
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Gold nanorods assisted photothermal therapy of bladder cancer in mice: A computational study on the effects of gold nanorods distribution at the centre, periphery, and surface of bladder cancer.
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Comput Methods Programs Biomed. 2023 Mar;230:107363. doi: 10.1016/j.cmpb.2023.107363. Epub 2023 Jan 21.
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