Diab Mohamed, Abu-Elsaoud Abdelghafar, Ghareeb Eman, Abd El-Azeem Eman, Elkelish Amr, Salama Mohamed
Pest Physiology Department, Plant Protection Research Institute, Agricultural Research Center, Giza, 12311, Egypt.
Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.
Sci Rep. 2025 Sep 12;15(1):32429. doi: 10.1038/s41598-025-15412-y.
Spodoptera frugiperda, known as the fall armyworm, is a highly destructive pest that greatly impacts worldwide agriculture, particularly maize and other key crops. Its rapid expansion and resistance to standard insecticides pose a significant threat to food security. As a result, effective and long-term pest management solutions are required. In this context, microbial biocontrol agents, such as Saccharomyces cerevisiae, offer an environmentally friendly alternative to chemical pesticides. This study investigates S. cerevisiae's efficiency as a biocontrol agent against S. frugiperda. The S. cerevisiae HA-NY4 strain was evaluated for larvicidal activity as well as its effect on insect metabolism and development. The results showed that S. cerevisiae HA-NY4 significantly increased larval mortality after 72 h of treatment. Furthermore, it caused metabolic abnormalities in the larva, including reduced protein synthesis, impaired carbohydrate metabolism, and developmental defects. These effects resulted in delayed pupation, lower pupal weight, and decreased adult emergence, thereby restricting the pest's reproductive potential. The main goal of this study was to evaluate the effectiveness of the S. cerevisiae HA-NY4 strain, thus providing a sustainable and environmentally friendly solution to manage S. frugiperda infestations.
草地贪夜蛾，又称秋粘虫，是一种极具破坏力的害虫，对全球农业，尤其是玉米和其他主要作物造成了极大影响。其迅速扩散以及对标准杀虫剂产生抗性，对粮食安全构成了重大威胁。因此，需要有效的长期害虫管理解决方案。在此背景下，诸如酿酒酵母等微生物生物防治剂为化学农药提供了一种环保替代方案。本研究调查了酿酒酵母作为防治草地贪夜蛾的生物防治剂的效率。对酿酒酵母HA-NY4菌株的杀幼虫活性及其对昆虫代谢和发育的影响进行了评估。结果表明，处理72小时后，酿酒酵母HA-NY4显著提高了幼虫死亡率。此外，它还导致幼虫出现代谢异常，包括蛋白质合成减少、碳水化合物代谢受损以及发育缺陷。这些影响导致化蛹延迟、蛹重降低和成虫羽化减少，从而限制了害虫的繁殖潜力。本研究的主要目的是评估酿酒酵母HA-NY4菌株的有效性，从而为管理草地贪夜蛾虫害提供一种可持续且环保的解决方案。
