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多西环素治疗沙眼衣原体感染的临床评估

[Clinical evaluation of doxycycline in the treatment of Chlamydia trachomatis infections].

作者信息

Saito I, Yokozawa M, Ono K

出版信息

Jpn J Antibiot. 1985 Nov;38(11):3169-78.

PMID:4094052
Abstract

Thirty male patients with nongonococcal urethritis and 7 female patients nongonococcal cervicitis were treated with 200 mg doxycycline (DOXY) daily over a period of 7 days. The microbiological cure rate in infections with C. trachomatis was 92.9% with the clinical effectiveness rate being 92.9%. The clinical effectiveness rate in nonchlamydial urethritis was 63.6%. There were no statistically demonstrable difference in clinical outcome between the group of the C. trachomatis positive patients and the C. trachomatis negative patients, both treated with DOXY. Side effects were observed in 2 cases (5.4%) who complained of gastrointestinal disorder, but no dizziness was observed.

摘要

30例男性非淋菌性尿道炎患者和7例女性非淋菌性宫颈炎患者接受了为期7天的治疗,每日口服200毫克强力霉素(DOXY)。沙眼衣原体感染的微生物学治愈率为92.9%,临床有效率为92.9%。非衣原体性尿道炎的临床有效率为63.6%。接受DOXY治疗的沙眼衣原体阳性患者组和沙眼衣原体阴性患者组之间,临床结果没有统计学上的显著差异。有2例(5.4%)出现副作用,主诉胃肠道不适,但未观察到头晕症状。

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