Socol Ioana Denisa, Abu-Awwad Ahmed, Socol Flavius George, Farcaș Simona Sorina, Abu-Awwad Simona-Alina, Dumitriu Bogdan-Ionel, Dumitriu Alina-Iasmina, Iacob Daniela, Vasile Daniela-Violeta, Andreescu Nicoleta Ioana
Doctoral School, University of Medicine and Pharmacy "Victor Babeş", Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Department XV-Discipline of Orthopedics-Traumatology, University of Medicine and Pharmacy "Victor Babeş", Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Healthcare (Basel). 2025 Sep 4;13(17):2211. doi: 10.3390/healthcare13172211.
: Maternal depression, anxiety, perceived stress, and resilience are recognized determinants of perinatal health, yet routine psychological screening is still uncommon in Romanian obstetric practice. This study examined how these four psychological factors relate to preterm birth, gestational hypertension, intra-uterine growth restriction (IUGR), and low birth weight in primiparous women. : In a cross-sectional study at a tertiary maternity center in Timișoara (February 2024-February 2025), 240 women at 20-28 weeks' gestation completed the Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder-7 (GAD-7), Perceived Stress Scale-10 (PSS-10), and Connor-Davidson Resilience Scale-25 (CD-RISC-25). Obstetric outcomes were abstracted from medical records. Pearson correlations described bivariate associations; multivariate logistic regression assessed independent effects after mutual adjustment. : Preterm birth occurred in 21% of pregnancies, gestational hypertension in 17%, IUGR in 15%, and low birth weight in 21%. Higher EPDS, GAD-7, and PSS-10 scores correlated positively with each complication (r = 0.19-0.36; < 0.02), whereas CD-RISC-25 scores showed inverse correlations (r = -0.22 to -0.29; ≤ 0.012). In the fully adjusted model, GAD-7 remained the only independent psychological predictor of the composite obstetric outcome (β = 0.047; 95% CI 0.010-0.083; = 0.013). Perceived stress approached significance; depression and resilience were no longer significant after adjustment. : Generalized anxiety was the most robust psychological determinant of adverse obstetric outcomes, with perceived stress, depression, and lower resilience showing contributory roles at the unadjusted level. Incorporating brief instruments such as the GAD-7, PSS-10, and CD-RISC-25 into routine prenatal care could facilitate early identification of at-risk pregnancies and inform targeted preventive interventions.
产妇抑郁、焦虑、感知压力和心理韧性是围产期健康的公认决定因素，但在罗马尼亚的产科实践中，常规心理筛查仍不常见。本研究调查了这四种心理因素与初产妇早产、妊娠期高血压、宫内生长受限（IUGR）和低出生体重之间的关系。
在蒂米什瓦拉一家三级妇产中心进行的一项横断面研究中（2024年2月至2025年2月），240名妊娠20 - 28周的妇女完成了爱丁堡产后抑郁量表（EPDS）、广泛性焦虑障碍量表 - 7（GAD - 7）、感知压力量表 - 10（PSS - 10）和康纳 - 戴维森心理韧性量表 - 25（CD - RISC - 25）。产科结局从医疗记录中提取。Pearson相关性描述了双变量关联；多因素逻辑回归评估了相互调整后的独立效应。
21%的妊娠发生早产，17%发生妊娠期高血压，15%发生宫内生长受限，21%出生体重低。较高的EPDS、GAD - 7和PSS - 10评分与每种并发症呈正相关（r = 0.19 - 0.36；P < 0.02），而CD - RISC - 25评分呈负相关（r = -0.22至 -0.29；P ≤ 0.012）。在完全调整模型中，GAD - 7仍然是复合产科结局的唯一独立心理预测因素（β = 0.047；95% CI 0.010 - 0.083；P = 0.013）。感知压力接近显著水平；调整后抑郁和心理韧性不再显著。
广泛性焦虑是不良产科结局最有力的心理决定因素，在未调整水平上，感知压力、抑郁和较低的心理韧性也显示出促成作用。将GAD - 7、PSS - 10和CD - RISC - 25等简短工具纳入常规产前护理可以促进对高危妊娠的早期识别，并为有针对性的预防干预提供依据。
