Lee Jeong In, Ngo Dac Hong An, Hwang Hong Pil, Han Young Min, Kwak Hyo Sung
Department of Medicine, Jeonbuk National University, Jeonju 54907, Republic of Korea.
Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University and Medical School, Jeonju 54907, Republic of Korea.
Diagnostics (Basel). 2025 Aug 24;15(17):2134. doi: 10.3390/diagnostics15172134.
: This study investigated the impact of aortoiliac geometry on thrombotic complication following aortic endovascular aneurysm repair (EVAR). : Data from 54 patients who received abdominal EVAR between January 2015 and December 2023, in which 18 developed unilateral iliac limb in-stent thrombus, were retrospectively reviewed. Clinical data, including cardiovascular risk factors, laboratory findings, and geometrical factors, including iliac diameter, sectional area, limb angles, and tortuosity, were collected. Aortoiliac geometry analyses were performed on the 3D model reconstructed from abdominal aortic computed tomography angiography (CTA) using semi-automated software (MIMICS version 25.0). : Compared to non-thrombotic limbs, thrombotic iliac limbs showed larger maximum diameters (17.48 ± 0.95 mm vs. 14.14 ± 0.62 mm, = 0.006), lower graft limb angles (117.52° ± 5.61° vs. 148.54° ± 4.31°, < 0.001), lower aortoiliac angles (123.48° ± 4.66° vs. 141.96° ± 4.76°, = 0.009), and higher iliac tortuosities (0.2 ± 0.03 vs. 0.12 ± 0.02, = 0.02). Paired comparisons between normal and diseased limbs in 18 patients with thrombotic events also showed statistical differences in terms of iliac limb maximum diameter, graft limb angle, aortoiliac angle, and iliac tortuosity. : Thrombosis formation following EVAR in iliac limbs was associated with limb diameter, graft limb angle, aortoiliac angle, and tortuosity.
本研究调查了腹主动脉瘤腔内修复术(EVAR)后,主髂动脉几何形态对血栓形成并发症的影响。回顾性分析了2015年1月至2023年12月期间接受腹部EVAR治疗的54例患者的数据,其中18例发生了单侧髂支支架内血栓形成。收集了临床数据,包括心血管危险因素、实验室检查结果,以及几何因素,如髂动脉直径、截面积、分支角度和迂曲度。使用半自动软件(MIMICS 25.0版)对从腹主动脉计算机断层扫描血管造影(CTA)重建的三维模型进行主髂动脉几何形态分析。与无血栓形成的分支相比,发生血栓的髂支最大直径更大(17.48±0.95mm对14.14±0.62mm,P=0.006),移植物分支角度更低(117.52°±5.61°对148.54°±4.31°,P<0.001),主髂动脉角度更低(123.48°±4.66°对141.96°±4.76°,P=0.009),髂动脉迂曲度更高(0.2±0.03对0.12±0.02,P=0.02)。18例发生血栓事件患者的正常与病变分支的配对比较在髂支最大直径、移植物分支角度、主髂动脉角度和髂动脉迂曲度方面也显示出统计学差异。EVAR术后髂支血栓形成与分支直径、移植物分支角度、主髂动脉角度和迂曲度有关。