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肥胖、血栓形成、静脉疾病、淋巴疾病和脂肪性水肿:肥胖医学协会(OMA)2023年临床实践声明(CPS)

Obesity, thrombosis, venous disease, lymphatic disease, and lipedema: An obesity medicine association (OMA) clinical practice statement (CPS) 2023.

作者信息

Bindlish Shagun, Ng Jennifer, Ghusn Wissam, Fitch Angela, Bays Harold Edward

机构信息

Adjunct Faculty Touro University, 7554 Dublin Blvd, Dublin, CA, USA.

Mount Sinai Icahn School of Medicine, Mount Sinai Primary Care Faculty Practice Associates, 234 E 85th St. 6th Fl, NY, NY, 10028, USA.

出版信息

Obes Pillars. 2023 Oct 19;8:100092. doi: 10.1016/j.obpill.2023.100092. eCollection 2023 Dec.

Abstract

BACKGROUND

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians with an overview on obesity, thrombosis, venous disease, lymphatic disease, and lipedema.

METHODS

The scientific support for this CPS is based upon published citations, clinical perspectives of OMA authors, and peer review by the Obesity Medicine Association leadership.

RESULTS

Topics in this CPS include obesity, thrombosis, venous disease, lymphatic disease, and lipedema. Obesity increases the risk of thrombosis and cardiovascular disease via fat mass and adiposopathic mechanisms. Treatment of thrombosis or thrombotic risk includes healthful nutrition, physical activity, and the requisite knowledge of how body weight affects anti-thrombotic medications. In addition to obesity-related thrombotic considerations of acute coronary syndrome and ischemic non-hemorrhagic stroke, this Clinical Practice Statement briefly reviews the diagnosis and management of clinically relevant presentations of deep vein thromboses, pulmonary embolism, chronic venous stasis, varicose veins, superficial thrombophlebitis, lipodermatosclerosis, corona phlebectatica, chronic thromboembolic pulmonary hypertension, iliofemoral venous obstruction, pelvic venous disorder, post-thrombotic syndrome, as well as lymphedema and lipedema - which should be included in the differential diagnosis of other edematous or enlargement disorders of the lower extremities.

CONCLUSIONS

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) on obesity, thrombosis, and venous/lymphatic disease is one of a series of OMA CPSs designed to assist clinicians in the care of patients with the disease of obesity.

摘要

背景

本肥胖医学协会(OMA)临床实践声明(CPS)旨在为临床医生提供有关肥胖、血栓形成、静脉疾病、淋巴疾病和脂肪性水肿的概述。

方法

本CPS的科学依据基于已发表的文献引用、OMA作者的临床观点以及肥胖医学协会领导层的同行评审。

结果

本CPS的主题包括肥胖、血栓形成、静脉疾病、淋巴疾病和脂肪性水肿。肥胖通过脂肪量和脂肪病理机制增加血栓形成和心血管疾病的风险。血栓形成或血栓形成风险的治疗包括健康的营养、体育活动以及体重如何影响抗血栓药物的必要知识。除了急性冠状动脉综合征和缺血性非出血性中风的肥胖相关血栓形成考虑因素外,本临床实践声明还简要回顾了深静脉血栓形成、肺栓塞、慢性静脉淤滞、静脉曲张、浅静脉血栓形成、脂性硬皮病、静脉周围晕、慢性血栓栓塞性肺动脉高压、髂股静脉阻塞、盆腔静脉疾病、血栓形成后综合征以及淋巴水肿和脂肪性水肿等临床相关表现的诊断和管理——这些应纳入下肢其他水肿或肿大疾病的鉴别诊断中。

结论

本肥胖医学协会(OMA)关于肥胖、血栓形成和静脉/淋巴疾病的临床实践声明(CPS)是一系列旨在协助临床医生护理肥胖患者的OMA CPS之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c56f/10728709/0c7fc79c5d0b/gr1.jpg

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