Samusyte Gintaute, Ciceliene Jolita, Pajediene Evelina, Stasaitis Kestutis, Petrikonis Kestutis, Bileviciute-Ljungar Indre
Department of Neurology, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Department of Emergency Medicine, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
J Clin Med. 2025 Sep 3;14(17):6222. doi: 10.3390/jcm14176222.
: The aim of this study was to investigate the natural course of a whiplash-associated disorder (WAD) in a Lithuanian population with low awareness of the condition. : In this controlled observational study, 45 participants, enrolled during the acute period after motor vehicle accident, and 50 matched controls were followed up at 8 months. Clinical evaluation of WAD grades was combined with self-scored questionnaires for pain, WAD symptoms, disability, emotional state, and cognitive impairment. The Quebec Task Force Questionnaire was used to assess persistence or development of new symptoms at follow-up. Demographic and sick leave data were collected. : The WAD group showed a significant improvement in clinical signs and self-rated scores for pain and disability after 8 months and became largely comparable to the control group. However, only 13 out of 45 WAD participants were symptom-free at follow-up. Persistent neck pain and dizziness/unsteadiness as well as newly developed cognitive complaints were more frequent in the WAD group compared to controls, each reported by around a third of individuals. Logistic regression showed that new cognitive symptoms could be predicted by nausea/vomiting in the acute period and persisting neck pain at follow-up. None of the participants remained on sick leave at follow-up. : In a country with low awareness of WAD, a larger proportion of individuals remain symptomatic months after acute whiplash injury but maintain their ability to work. The emergence of new cognitive complaints may suggest concomitant central nervous system involvement.
本研究的目的是在立陶宛一个对挥鞭样损伤相关疾病(WAD)认知度较低的人群中,调查该疾病的自然病程。
在这项对照观察性研究中,对45名在机动车事故急性期入组的参与者以及50名匹配的对照组进行了8个月的随访。WAD分级的临床评估与疼痛、WAD症状、残疾、情绪状态和认知障碍的自评问卷相结合。使用魁北克工作组问卷评估随访时新症状的持续或出现情况。收集了人口统计学和病假数据。
WAD组在8个月后临床体征以及疼痛和残疾的自评分数有显著改善,在很大程度上与对照组相当。然而,45名WAD参与者中只有13人在随访时无症状。与对照组相比,WAD组中持续性颈部疼痛、头晕/不稳以及新出现的认知主诉更为常见,每组约有三分之一的个体报告有这些症状。逻辑回归显示,急性期的恶心/呕吐和随访时持续的颈部疼痛可预测新的认知症状。随访时没有参与者仍在休病假。
在一个对WAD认知度较低的国家,很大一部分个体在急性挥鞭样损伤数月后仍有症状,但仍保持工作能力。新出现的认知主诉可能提示伴有中枢神经系统受累。