Constantin George-Dumitru, Veja Ioana, Niculescu Serban Talpos, Mazilescu Crisanta-Alina, Hoinoiu Teodora, Buda Valentina Oana, Oancea Roxana
Discipline of Clinical Practical Skills, Department I Nursing, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Department of Dental Medicine, Faculty of Dentistry, "Vasile Goldiș" Western University of Arad, 310025 Arad, Romania.
J Clin Med. 2025 Sep 4;14(17):6256. doi: 10.3390/jcm14176256.
Hospital-based data can complement registry estimates for cranio-maxillofacial (CMF) oncology, particularly in under-reported regions. We aimed to describe the institutional case-mix of CMF tumor diagnoses, standardized to ICD-10 sites, and to quantify trends using visit-normalized indicators. We conducted a retrospective, observational, single-center, hospital-based study of diagnosis-level encounters (2012-2016). Diagnoses were recoded to ICD-10 and restricted to CMF sites (lip, oral cavity, major salivary glands, oropharynx/hypopharynx, nasal cavity/middle ear, paranasal sinuses, eye/adnexa). The primary indicator uses a strict CMF set (malignant CMF codes plus D00.0 and D14.1); odontogenic cysts and non-neoplastic jaw lesions (K09-K10) were excluded, while benign CMF neoplasms are reported descriptively for site distributions. We identified 2729 malignant CMF diagnoses over 2012-2016, peaking in 2014 ( = 751) and lowest in 2016 ( = 367). The combined malignant rate (per 1000 total visits) was 30.6, 43.9, 52.6, 34.4, and 26.7 for 2012→2016. The proportion of malignancies within the strict CMF set was 99.2%, 97.3%, 97.9%, 96.8%, and 95.1%, respectively (overall 97.4%). The most frequent malignant sites cumulatively were the palate ( = 416), parotid gland ( = 376), floor of mouth ( = 344), gingiva ( = 282), and mouth, unspecified ( = 179). After ICD-10 recoding and restriction to CMF sites, malignant tumors predominated within the institutional, diagnosis-level case-mix, with a 2014 peak followed by a decline. These indicators are case-mix monitors and not population incidences; interpretation should consider coding practices and service-mix changes across years.
基于医院的数据可以补充颅颌面（CMF）肿瘤学登记处的估计数据，特别是在报告不足的地区。我们旨在描述CMF肿瘤诊断的机构病例组合情况，并按照国际疾病分类第10版（ICD-10）的部位进行标准化，同时使用就诊标准化指标来量化趋势。我们对诊断层面的就诊情况进行了一项回顾性、观察性、单中心、基于医院的研究（2012 - 2016年）。诊断结果被重新编码为ICD-10，并限定在CMF部位（嘴唇、口腔、主要唾液腺、口咽/下咽、鼻腔/中耳、鼻窦、眼附属器）。主要指标使用严格的CMF集合（恶性CMF编码加上D00.0和D14.1）；牙源性囊肿和非肿瘤性颌骨病变（K09 - K10）被排除在外，而良性CMF肿瘤则按部位分布进行描述性报告。我们在2012 - 2016年期间共识别出2729例恶性CMF诊断病例，2014年达到峰值（751例），2016年最低（367例）。2012年至2016年的综合恶性率（每1000次总就诊）分别为30.6、43.9、52.6、34.4和26.7。在严格的CMF集合中，恶性肿瘤的比例分别为99.2%、97.3%、97.9%、96.8%和95.1%（总体为97.4%）。累计最常见的恶性部位是腭部（416例）、腮腺（376例）、口底（344例）、牙龈（282例）和未特指的口腔（179例）。经过ICD-10重新编码并限定在CMF部位后，恶性肿瘤在机构层面的诊断病例组合中占主导地位，2014年达到峰值后呈下降趋势。这些指标是病例组合监测指标，而非人群发病率；解读时应考虑编码实践和多年来服务组合的变化。
