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早期结直肠癌非根治性内镜黏膜下剥离术后的挽救性手术:综述

Salvage Surgery After Non-Curative Endoscopic Submucosal Dissection for Early Colorectal Cancer: A Comprehensive Review.

作者信息

Aigner Felix, Skias Christoph, Duller David, Wisiak Sebastian, Strohmeyer Karin, Horvath Zoltan, Koter Nicole

机构信息

Department of Surgery, St. John of God Hospital Graz, Marschallgasse 12, 8020 Graz, Austria.

出版信息

J Clin Med. 2025 Sep 8;14(17):6343. doi: 10.3390/jcm14176343.

Abstract

Endoscopic submucosal dissection (ESD) has emerged as a minimally invasive technique for treating early colorectal cancer (CRC), offering the potential for en bloc resection and precise histopathological assessment. However, when ESD results in non-curative outcomes-characterized by factors such as positive margins, deep submucosal invasion, or lymphovascular invasion-salvage surgery becomes a critical consideration. This review synthesizes current evidence on the indications, timing, surgical approaches, outcomes, and future directions of salvage surgery following non-curative ESD in early CRC.

摘要

内镜黏膜下剥离术(ESD)已成为治疗早期结直肠癌(CRC)的一种微创技术,具有整块切除和精确组织病理学评估的潜力。然而,当ESD导致非治愈性结果时(以切缘阳性、黏膜下深层浸润或脉管浸润等因素为特征),挽救性手术就成为一个关键的考虑因素。本综述综合了目前关于早期CRC非治愈性ESD后挽救性手术的适应证、时机、手术方式、结局及未来方向的证据。

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