Aigner Felix, Skias Christoph, Duller David, Wisiak Sebastian, Strohmeyer Karin, Horvath Zoltan, Koter Nicole
Department of Surgery, St. John of God Hospital Graz, Marschallgasse 12, 8020 Graz, Austria.
J Clin Med. 2025 Sep 8;14(17):6343. doi: 10.3390/jcm14176343.
Endoscopic submucosal dissection (ESD) has emerged as a minimally invasive technique for treating early colorectal cancer (CRC), offering the potential for en bloc resection and precise histopathological assessment. However, when ESD results in non-curative outcomes-characterized by factors such as positive margins, deep submucosal invasion, or lymphovascular invasion-salvage surgery becomes a critical consideration. This review synthesizes current evidence on the indications, timing, surgical approaches, outcomes, and future directions of salvage surgery following non-curative ESD in early CRC.
内镜黏膜下剥离术（ESD）已成为治疗早期结直肠癌（CRC）的一种微创技术，具有整块切除和精确组织病理学评估的潜力。然而，当ESD导致非治愈性结果时（以切缘阳性、黏膜下深层浸润或脉管浸润等因素为特征），挽救性手术就成为一个关键的考虑因素。本综述综合了目前关于早期CRC非治愈性ESD后挽救性手术的适应证、时机、手术方式、结局及未来方向的证据。
