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避孕药之外:根据不同依从水平揭示匈牙利孕妇产前微量营养素摄入特征

Beyond the Pill: Unveiling the Characteristics of Prenatal Micronutrient Consumption Among Hungarian Pregnant Women According to Different Levels of Adherence.

作者信息

Polanek Evelin, Rárosi Ferenc, Béky Csenge Fruzsina, Molnár Regina, Németh Gábor, Orvos Hajnalka, Paulik Edit, Szabó Andrea

机构信息

Doctoral School of Experimental and Preventive Medicine, University of Szeged, 6720 Szeged, Hungary.

Department of Medical Physics and Informatics, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.

出版信息

Nutrients. 2025 Aug 23;17(17):2732. doi: 10.3390/nu17172732.

Abstract

: There is clear evidence that maternal micronutrient deficiencies result in adverse maternal and fetal health outcomes. Therefore, corrective supplementation should be considered when dietary intake is insufficient, particularly for vitamin D (VD), omega-3 fatty acids (O3), folic acid (FA), or prenatal multiple micronutrient products (PMM). Despite its significance, intake patterns in Hungary remain largely unexplored, and evaluating adherence to recommended intake levels would be of even greater importance. This is the first Hungarian study to provide a comprehensive overview of the frequency and adherence patterns of micronutrient supplementation among pregnant women, while also analyzing their association with predictors and outcomes. : This cross-sectional study involved 300 pregnant women who delivered in a university hospital. Data were collected using a self-reported questionnaire and clinical maternal and neonatal records. : The prevalence of FA, VD, O3, and PMM intake among the participants was 89.0%, 76.4%, 58.7%, and 67.6%, respectively. However, adherence to recommendations was notably lower: 41.1% for VD, 37.5% for O3, 36% for PMM, and 31% for FA. Higher adherence was associated with older maternal age, higher educational level, county town residence, planned pregnancy, primiparity, previous spontaneous abortion, and early initiation of antenatal care. Our findings refute concerns about the obesogenic effect of supplementation for both mothers and newborns. FA intake correlated with a lower likelihood of cesarean section, while O3 use was associated with improved uterine contractility and reduced risk of gestational diabetes mellitus. : Our study underscores the need for individualized counselling on micronutrient supplementation, with particular emphasis on appropriate timing, dosage, and potential benefits.

摘要

有明确证据表明,孕产妇微量营养素缺乏会导致不良的孕产妇和胎儿健康结局。因此,当饮食摄入不足时,应考虑进行纠正性补充,特别是对于维生素D(VD)、ω-3脂肪酸(O3)、叶酸(FA)或产前多种微量营养素产品(PMM)。尽管其意义重大,但匈牙利的摄入模式在很大程度上仍未得到探索,评估对推荐摄入量的依从性将更为重要。这是第一项全面概述匈牙利孕妇微量营养素补充频率和依从模式的研究,同时还分析了它们与预测因素和结局的关联。

这项横断面研究涉及300名在大学医院分娩的孕妇。数据通过自我报告问卷以及孕产妇和新生儿临床记录收集。

参与者中FA、VD、O3和PMM的摄入率分别为89.0%、76.4%、58.7%和67.6%。然而,对推荐摄入量的依从性明显较低:VD为41.1%,O3为37.5%,PMM为36%,FA为31%。较高的依从性与产妇年龄较大、教育水平较高、居住在县城、计划怀孕、初产、既往自然流产以及早期开始产前护理有关。我们的研究结果驳斥了关于补充剂对母亲和新生儿产生致肥胖作用的担忧。FA摄入与剖宫产可能性较低相关,而使用O3与子宫收缩力改善和妊娠期糖尿病风险降低有关。

我们的研究强调了对微量营养素补充进行个性化咨询的必要性,尤其要强调适当的时间、剂量和潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9590/12429979/70060de84f38/nutrients-17-02732-g001.jpg

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