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营养对使用和未使用激素疗法的子宫内膜异位症患者不适症状的影响。

The Impact of Nutrition on Endometriosis Complaints in Patients Using and Not Using Hormone Therapy.

作者信息

Pelc Agnieszka, Polak-Szczybyło Ewelina

机构信息

Department of Physiotherapy, Institute of Health Sciences and Psychology, Collegium Medicum, University of Rzeszów, 35-959 Rzeszow, Poland.

Department of Dietetics, Faculty of Health Sciences and Psychology, Collegium Medicum, University of Rzeszów, ul. Warzywna 1a, 35-959 Rzeszow, Poland.

出版信息

Nutrients. 2025 Sep 6;17(17):2889. doi: 10.3390/nu17172889.

Abstract

BACKGROUND

Endometriosis is a chronic inflammatory disease marked by the presence of endometrial tissue outside the uterus. Main symptoms include pain in the sacrum, pelvis, and abdomen, occurring at various stages of the menstrual cycle or during intercourse. These symptoms can severely affect daily functioning and quality of life.

METHODS

The study involved 200 women aged 18-47, divided into two groups. The WHT group (N = 100) included women with endometriosis not receiving hormone therapy, and the HT group (N = 100) included women undergoing hormone treatment. An anonymous questionnaire was used, comprising a VAS, the FFQ-6 food frequency questionnaire, and questions regarding menstruation-related symptoms and effects.

RESULTS

Women in the HT group reported higher pain levels (Me = 8.0 vs. 7.0) and more frequent negative impacts on academic/work performance ( = 0.008) than the WHT group, who reported higher work attendance ( = 0.043). In the WHT group, consumption of sugar, honey ( = 0.019), sweet cereals ( = 0.023), and sweetened beverages ( = 0.036) was associated with absences and concentration difficulties ( = 0.010). In contrast, in the HT group, those reporting absences consumed more nuts and vegetables ( = 0.024; = 0.003).

CONCLUSIONS

Women with endometriosis undergoing hormone therapy report more severe pain and more frequent disruptions in daily functioning. Both hormone therapy and diet significantly influence the intensity of menstrual symptoms as well as the ability to function professionally and socially.

摘要

背景

子宫内膜异位症是一种慢性炎症性疾病,其特征是子宫外存在子宫内膜组织。主要症状包括骶骨、骨盆和腹部疼痛,在月经周期的不同阶段或性交时出现。这些症状会严重影响日常功能和生活质量。

方法

该研究纳入了200名年龄在18 - 47岁之间的女性,分为两组。WHT组(N = 100)包括未接受激素治疗的子宫内膜异位症女性,HT组(N = 100)包括正在接受激素治疗的女性。使用了一份匿名问卷,包括视觉模拟评分法(VAS)、FFQ - 6食物频率问卷以及关于月经相关症状和影响的问题。

结果

HT组女性报告的疼痛程度更高(中位数 = 8.0对7.0),对学业/工作表现的负面影响更频繁(P = 0.008),而WHT组报告的工作出勤率更高(P = 0.043)。在WHT组中,糖、蜂蜜(P = 0.019)、甜谷物(P = 0.023)和含糖饮料(P = 0.036)的摄入与缺勤和注意力不集中有关(P = 0.010)。相比之下,在HT组中,报告缺勤的人摄入了更多的坚果和蔬菜(P = 0.024;P = 0.003)。

结论

接受激素治疗的子宫内膜异位症女性报告有更严重的疼痛和更频繁的日常功能干扰。激素治疗和饮食都会显著影响月经症状的强度以及职业和社交功能。

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