Tootell R B, Silverman M S
J Neurosci Methods. 1985 Nov-Dec;15(3):177-90. doi: 10.1016/0165-0270(85)90097-4.
Two procedures are described which allow cortical grey matter to be unfolded and flattened. Tangential sections of the flat-mounted tissue can reveal clear histological views of horizontal variations in cortical structure and function; these anatomical variations would be hard to see in sections cut by conventional techniques. Examples are presented from non-human primate tissue, but the technique has also been used successfully in a number of other mammalian species, including man. Advantages and disadvantages of the various methods for extracting topographical patterns from the cortex are discussed.
本文描述了两种可使皮质灰质展开并变平的方法。平铺组织的切线切片能够清晰显示皮质结构和功能水平变化的组织学视图；这些解剖学变化在传统技术切割的切片中很难看到。文中给出了来自非人灵长类动物组织的示例，但该技术也已在包括人类在内的许多其他哺乳动物物种中成功应用。本文还讨论了从皮质提取地形模式的各种方法的优缺点。
