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酒精化雄性和雌性大鼠后代运动系统高级部分的神经元及神经间连接的变化

Changes in neurons and interneural connections of the higher sections of the motor system in the progeny of alcoholized male and female rats.

作者信息

Popova E N, Frumkina L E

出版信息

Neurosci Behav Physiol. 1985 Nov-Dec;15(6):476-9. doi: 10.1007/BF01184256.

Abstract

We have studied the effects of long-term alcoholic intoxication of male and female rats on the structural development of the sensory motor cortex and the caudate nucleus in 21-day-old rats (their progeny). Using light microscopy and morphometry we observed a delay in the maturation of neurons and their dendrites, and also dystrophic changes in the nerve structures in the experimental animals. The morphological changes observed show that alcoholic intoxication of parents leads to negative effects on postnatal development of their progeny.

摘要

我们研究了雄性和雌性大鼠长期酒精中毒对21日龄大鼠(它们的后代)感觉运动皮层和尾状核结构发育的影响。通过光学显微镜和形态测量法,我们观察到实验动物中神经元及其树突成熟延迟,以及神经结构的营养不良性变化。观察到的形态学变化表明,亲本的酒精中毒会对其后代的出生后发育产生负面影响。

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