Pavlovskaia N I, Kaiumov B P
Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(10):1557-60.
Alcohol was given to rats in a dose of 1 ml of 35-per-cent ethanol per 100 g body weight daily for 20, 40, 60, 90, and 120 days. Each period of the alcoholic intoxication was characterized by specific changes in the neurons, glia, and capillaries. Characteristic of initial periods of the alcoholic intoxication were reactive changes in the neurons: an important place in these changes belonged to compensatory-adaptive processes. The longer the period of the alcoholic intoxication, the greater the scope of the morphological changes, up to dystrophic lesions and grave forms of cell damage. A certain relationship between vascular changes and neuronal damages were noted.
每天给大鼠按每100克体重注射1毫升35%的乙醇，持续20、40、60、90和120天。每个酒精中毒阶段的特点是神经元、神经胶质和毛细血管发生特定变化。酒精中毒初期的特点是神经元的反应性变化：这些变化中一个重要的方面属于代偿 - 适应过程。酒精中毒的时间越长，形态学变化的范围就越大，直至出现营养不良性病变和严重的细胞损伤形式。还注意到血管变化与神经元损伤之间存在一定关系。
