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杏仁核在评估条件刺激的生物学意义中的作用。

Involvement of the amygdala in evaluating the biological significance of conditioned stimuli.

作者信息

Suvorov N F, Danilova L K, Shefer S I, Shuvaev V T

出版信息

Neurosci Behav Physiol. 1985 Nov-Dec;15(6):494-501. doi: 10.1007/BF01184260.

DOI:10.1007/BF01184260
PMID:4094682
Abstract

The destruction of the amygdala in cats and dogs causes the animals to stop responding adequately to signals of various biological significance; the curves of change in the amplitude and probability of appearance of EPs in the sensorimotor cortex lose the maxima characteristic of intact animals at frequencies of 0.8, 1.6, and in the band from 2.0 to 3.0 kHz, which are the format frequencies of certain communicational signals in cats. The assumption of a signal (food) significance by an indifferent stimulus, earlier without any biological meaning, finds reflection in the neuronal activity of the amygdala, which begins to respond to this signal as if to an unconditioned stimulus. On the basis of the above factors, the role of the amygdala is discussed in the evolution of the biological significance of conditioned stimuli and the differentiation of the afferent influences that reach it.

摘要

猫和狗的杏仁核被破坏后,会导致动物对各种具有生物学意义的信号不再能做出充分反应;感觉运动皮层中诱发电位(EP)的振幅和出现概率的变化曲线,在0.8、1.6以及2.0至3.0千赫兹频段(这些是猫的某些交流信号的形式频率)时,失去了正常动物所特有的最大值。原本无任何生物学意义的中性刺激被赋予信号(食物)意义后,会在杏仁核的神经元活动中有所体现,此时杏仁核开始像对非条件刺激一样对该信号做出反应。基于上述因素,讨论了杏仁核在条件刺激生物学意义的进化以及到达杏仁核的传入影响的分化过程中的作用。

相似文献

1
Involvement of the amygdala in evaluating the biological significance of conditioned stimuli.杏仁核在评估条件刺激的生物学意义中的作用。
Neurosci Behav Physiol. 1985 Nov-Dec;15(6):494-501. doi: 10.1007/BF01184260.
2
[Role of the amygdala in the evaluation of the biological significance of conditioned stimuli].杏仁核在评估条件刺激生物学意义中的作用
Fiziol Zh SSSR Im I M Sechenova. 1983 Mar;69(3):304-12.
3
[The correlations of the evoked activity of the auditory cortex and amygdala in cats during conditioned reflex activities].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Sep-Oct;41(5):955-62.
4
[Analysis of the neuronal activity of cortical-subcortical structures of a conditioned reflex].[条件反射的皮层 - 皮层下结构的神经元活动分析]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1978 May-Jun;28(3):557-65.
5
Correlation relationships of evoked activity of the auditory cortex and the amygdalae of cats during conditioned reflex activity.猫在条件反射活动期间听觉皮层与杏仁核诱发活动的相关关系。
Neurosci Behav Physiol. 1992 Nov-Dec;22(6):512-8. doi: 10.1007/BF01185441.
6
Electrophysiological evidence for formation of new corticorubral synapses associated with classical conditioning in the cat.猫中与经典条件反射相关的新皮质-红核突触形成的电生理证据。
Exp Brain Res. 1994;99(2):277-88. doi: 10.1007/BF00239594.
7
Fear conditioning enhances different temporal components of tone-evoked spike trains in auditory cortex and lateral amygdala.恐惧条件反射增强了听觉皮层和外侧杏仁核中音调诱发的尖峰序列的不同时间成分。
Neuron. 1997 Sep;19(3):613-24. doi: 10.1016/s0896-6273(00)80375-x.
8
[Changes in evoked potentials during differentiation inhibition].[分化抑制过程中诱发电位的变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1979 Nov-Dec;29(6):1151-6.
9
[The effect of destruction of the amygdala and pallidal region on a conditioned food-getting reflex and cortical evoked potentials to acoustic stimulation].
Fiziol Zh. 1975 Jan-Feb;21(1):29-36.
10
[Responses of the neurons of the parietal associative cortex of the cat brain to indifferent and conditioned acoustic stimuli].[猫脑顶叶联合皮质神经元对非条件和条件听觉刺激的反应]
Neirofiziologiia. 1988;20(5):637-45.

本文引用的文献

1
AMYGDALA UNITARY ACTIVITY IN THE UNRESTRAINED CAT.自由活动猫的杏仁核单位活动
Electroencephalogr Clin Neurophysiol. 1963 Aug;15:637-50. doi: 10.1016/0013-4694(63)90115-9.
2
Neural associations of the amygdaloid complex in the monkey.猴子杏仁核复合体的神经关联
Brain. 1962 Sep;85:505-20. doi: 10.1093/brain/85.3.505.
3
Modality and topographic properties of single neurons of cat's somatic sensory cortex.猫躯体感觉皮层单个神经元的模态和地形学特性
J Neurophysiol. 1957 Jul;20(4):408-34. doi: 10.1152/jn.1957.20.4.408.
4
Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain.通过电刺激大鼠脑的隔区及其他区域产生的阳性强化。
J Comp Physiol Psychol. 1954 Dec;47(6):419-27. doi: 10.1037/h0058775.
5
[Role of the lateral amygdaloid nucleus in performing alimentary instrumental reactions in rats].[外侧杏仁核在大鼠进食性工具性反应中的作用]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1981;31(2):271-5.
6
[Spatial hearing: location of stationary and moving sources of sound].[空间听觉:静止和移动声源的定位]
Usp Fiziol Nauk. 1981 Oct-Dec;12(4):28-51.
7
Complex swnsory properties of certain amygadala units in the freely moving cat.自由活动猫中某些杏仁核神经元的复杂感觉特性
Exp Neurol. 1969 Mar;23(3):384-98. doi: 10.1016/0014-4886(69)90086-7.
8
[Differentiated and extinctive inhibition during stimulation and ablation of the basolateral section of the amygdala].[杏仁核基底外侧部刺激与损毁过程中的分化抑制和消退抑制]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1972 Mar-Apr;22(2):253-9.
9
[Formation of alimentary conditioned reflexes in amygdalectomized dogs].[切除杏仁核的狗的食物性条件反射的形成]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1974 Nov-Dec;24(6):1155-64.
10
[Dynamics of disorders of internal inhibition following damage to the caudate nuclei and amygdala].[尾状核和杏仁核损伤后内抑制障碍的动态变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1971 Nov-Dec;21(6):1131-9.