Schweitzer L, Cant N B
Neuroscience. 1985 Dec;16(4):969-78. doi: 10.1016/0306-4522(85)90109-5.
The shapes of the apical and basal dendritic fields of the fusiform cells in the dorsal cochlear nucleus of the hamster were analyzed quantitatively. Measurements of the cross-sectional areas of the dendritic fields in planes parallel and perpendicular to planes occupied by the cochlear nerve axons revealed that the apical dendrites have a preferential orientation with respect to the cochlear planes. No consistent orientation of the basal dendrites was apparent. The orientation of the apical dendrites is not present in the neonatal hamster; rather, it develops gradually and is not fully established until after postnatal day 25. Since the cochlear fibers grow into the dorsal cochlear nucleus, establish contacts and become functional before day 25, the presence of the cochlear input might be a prerequisite for the development of oriented dendritic trees. In adult hamsters that have had their cochlear input eliminated during infancy, the apical dendritic trees of the fusiform cells are not oriented normally. The results suggest that the presence of the afferent input is necessary for the differential growth that leads to the development of oriented dendritic trees.
对仓鼠耳蜗背侧核中梭形细胞的顶端和基部树突野的形状进行了定量分析。在与耳蜗神经轴突所在平面平行和垂直的平面上测量树突野的横截面积，结果显示顶端树突相对于耳蜗平面具有优先取向。基部树突没有明显一致的取向。新生仓鼠不存在顶端树突的这种取向；相反，它是逐渐发展的，直到出生后第25天才完全形成。由于耳蜗纤维在出生后第25天之前长入耳蜗背侧核、建立联系并开始发挥功能，所以耳蜗输入的存在可能是定向树突树发育的一个先决条件。在婴儿期消除了耳蜗输入的成年仓鼠中，梭形细胞的顶端树突树没有正常取向。这些结果表明，传入输入的存在对于导致定向树突树发育的差异性生长是必要的。
