Whitmore W F, Batata M A, Hilaris B S, Reddy G N, Unal A, Ghoneim M A, Grabstald H, Chu F
Cancer. 1977 Sep;40(3):1077-86. doi: 10.1002/1097-0142(197709)40:3<1077::aid-cncr2820400316>3.0.co;2-r.
This report surveys the results of two programs of preoperative irradiation with radical cystectomy for bladder cancer in 205 patients. Irradiating the true pelvis to 4000 rads in 4 weeks with radical cystectomy after 6 weeks was implemented in 119 patients (Group 1) from 1959 to 1965; 2000 rads given in 1 week to the true pelvis and radical cystectomy within the following week was implemented in 86 patients (Group 2) from 1966 to 1970. Determinate survival without evidence of recurrence at 5 years was 43% in Group 1 and 42% in Group 2. Mortality with recurrence of bladder cancer in 5 or more years was 44% in group 1 and 42% in group 2. Pelvic complications occurred in 13% of group 1 and 9% of group 2.
本报告调查了205例膀胱癌患者接受的两项术前放疗联合根治性膀胱切除术方案的结果。1959年至1965年，对119例患者（第1组）进行4周内对真骨盆照射4000拉德，6周后行根治性膀胱切除术；1966年至1970年，对86例患者（第2组）在1周内对真骨盆给予2000拉德照射，并在接下来的一周内行根治性膀胱切除术。第1组5年无复发迹象的确定生存率为43%，第2组为42%。第1组5年及以上膀胱癌复发的死亡率为44%，第2组为42%。第1组13%的患者出现盆腔并发症，第2组为9%。
