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伴有肛周多汗症的肛提肌综合征的非典型表现:病例系列

Atypical Presentations of Levator Ani Syndrome With Perianal Hyperhidrosis: A Case Series.

作者信息

Gupta Riya, Jencks Kara J, Damianos John A, Wang Xiao Jing Iris

机构信息

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

出版信息

ACG Case Rep J. 2025 Sep 11;12(9):e01826. doi: 10.14309/crj.0000000000001826. eCollection 2025 Sep.

DOI:10.14309/crj.0000000000001826
PMID:40948587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12431760/
Abstract

Levator ani syndrome (LAS) explains up to 7.4% of anorectal pain cases. Classic symptoms include rectal pain or pressure with sitting. We present 2 patients, ages 32 and 25 years, presenting initially with "diarrhea" and perianal hyperhidrosis. History revealed rectal discomfort, tenesmus, urgency, and sensation of incomplete evacuation. Puborectalis tenderness was present on digital rectal examination. Therapies were tailored to each patient, including pelvic floor physical therapy with biofeedback, bowel regulation, rectal diazepam, and ileostomy. These presentations offer insights into potential pathophysiological mechanisms in LAS and highlight the importance of considering LAS in non-pain presentations.

摘要

耻骨直肠肌综合征(LAS)可解释高达7.4%的肛肠疼痛病例。典型症状包括坐位时直肠疼痛或有压迫感。我们报告2例患者,年龄分别为32岁和25岁,最初表现为“腹泻”和肛周多汗。病史显示有直肠不适、里急后重、便急和排便不尽感。直肠指检时有耻骨直肠肌压痛。针对每位患者进行了个体化治疗,包括盆底生物反馈物理治疗、肠道调节、直肠用安定和回肠造口术。这些病例展示了对LAS潜在病理生理机制的见解,并强调了在非疼痛表现中考虑LAS的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbb/12431760/efb5ec269a43/ac9-12-e01826-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbb/12431760/efb5ec269a43/ac9-12-e01826-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbb/12431760/efb5ec269a43/ac9-12-e01826-g001.jpg

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本文引用的文献

1
Pathoetiology of Levator Ani Syndrome and Its Treatment With Translumbosacral Neuromodulation Therapy.肛提肌综合征的发病机制及其经腰骶神经调节治疗。
Am J Gastroenterol. 2023 Dec 1;118(12):2242-2246. doi: 10.14309/ajg.0000000000002394. Epub 2023 Jul 7.
2
Levator Ani Syndrome Presenting with Vaginal Pain.肛提肌综合征致阴道疼痛
BMJ Case Rep. 2023 May 4;16(5):e255190. doi: 10.1136/bcr-2023-255190.
3
ACG Clinical Guidelines: Management of Benign Anorectal Disorders.ACG 临床指南:良性肛肠疾病的管理。
Am J Gastroenterol. 2021 Oct 1;116(10):1987-2008. doi: 10.14309/ajg.0000000000001507.
4
Functional Anorectal Disorders.功能性肛门直肠疾病
Gastroenterology. 2016 Mar 25. doi: 10.1053/j.gastro.2016.02.009.
5
Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV.功能性胃肠疾病:历史、病理生理学、临床特征与罗马IV标准
Gastroenterology. 2016 Feb 19. doi: 10.1053/j.gastro.2016.02.032.
6
Biofeedback is superior to electrogalvanic stimulation and massage for treatment of levator ani syndrome.生物反馈疗法优于电刺激和按摩,可用于治疗肛提肌综合征。
Gastroenterology. 2010 Apr;138(4):1321-9. doi: 10.1053/j.gastro.2009.12.040. Epub 2010 Jan 4.
7
Clinical trial: effects of botulinum toxin on Levator ani syndrome--a double-blind, placebo-controlled study.临床试验:肉毒杆菌毒素对提肛肌综合征的影响——一项双盲、安慰剂对照研究。
Aliment Pharmacol Ther. 2009 May 1;29(9):985-91. doi: 10.1111/j.1365-2036.2009.03964.x. Epub 2009 Feb 13.
8
Functional and chronic anorectal and pelvic pain disorders.功能性及慢性肛门直肠和盆腔疼痛障碍
Gastroenterol Clin North Am. 2008 Sep;37(3):685-96, ix. doi: 10.1016/j.gtc.2008.06.002.
9
Psychometric profiles and hypothalamic-pituitary-adrenal axis function in men with chronic prostatitis/chronic pelvic pain syndrome.慢性前列腺炎/慢性盆腔疼痛综合征男性的心理测量特征与下丘脑-垂体-肾上腺轴功能
J Urol. 2008 Mar;179(3):956-60. doi: 10.1016/j.juro.2007.10.084. Epub 2008 Jan 22.
10
Comparison study between electrogalvanic stimulation and local injection therapy in levator ani syndrome.耻骨直肠肌综合征的电刺激与局部注射治疗的对比研究
Int J Colorectal Dis. 2005 May;20(3):272-6. doi: 10.1007/s00384-004-0662-9. Epub 2004 Oct 30.