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1
Mepolizumab treatment in a child with inherited TYK2 deficiency.美泊利单抗治疗一名患有遗传性酪氨酸激酶2缺乏症的儿童。
J Hum Immun. 2025 Sep;1(3). doi: 10.70962/jhi.20250106. Epub 2025 Jul 29.
2
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A new heterozygous TYK2 gene mutation: Case report and review of the literature.一种新的杂合型酪氨酸激酶2(TYK2)基因突变:病例报告及文献综述
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本文引用的文献

1
Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome.人类酪氨酸激酶2缺乏症:无高免疫球蛋白E综合征的分枝杆菌和病毒感染。
J Exp Med. 2015 Sep 21;212(10):1641-62. doi: 10.1084/jem.20140280. Epub 2015 Aug 24.
2
Mepolizumab treatment in patients with severe eosinophilic asthma.美泊利珠单抗治疗严重嗜酸性粒细胞性哮喘患者。
N Engl J Med. 2014 Sep 25;371(13):1198-207. doi: 10.1056/NEJMoa1403290. Epub 2014 Sep 8.
3
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity.人类酪氨酸激酶2缺陷揭示了其在先天免疫和获得性免疫相关的多种细胞因子信号传导中的必要作用。
Immunity. 2006 Nov;25(5):745-55. doi: 10.1016/j.immuni.2006.09.009.
4
Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice.酪氨酸激酶2缺陷小鼠中Th2细胞介导的过敏性炎症增强。
J Immunol. 2003 Jan 15;170(2):1077-83. doi: 10.4049/jimmunol.170.2.1077.

Mepolizumab treatment in a child with inherited TYK2 deficiency.

作者信息

Alimi Aurélia, Wanin Stephanie, Boisson-Dupuis Stéphanie, Bastard Paul

机构信息

Department of Pediatric Hematology, Armand Trousseau University Hospital, Groupe Hospitalier Universitaire, AP-HP Sorbonne-University, Paris, France.

Department of Pediatric Allergology, Armand Trousseau University Hospital, Groupe Hospitalier Universitaire, AP-HP Sorbonne-University, Paris, France.

出版信息

J Hum Immun. 2025 Sep;1(3). doi: 10.70962/jhi.20250106. Epub 2025 Jul 29.

DOI:10.70962/jhi.20250106
PMID:40949057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12425477/
Abstract
摘要