Della Giustina E, Forese S, Pace P
Pediatr Med Chir. 1985 Mar-Apr;7(2):195-201.
One hundred forty six children having suffered bacterial meningitis at any age have been collected and retrospectively studied over a period of a twenty year survey (1960 to 1980). In our series we can confirm the prominent epidemiologic and clinical features emerging from the literature. It is notewborty to outline the great percentage of cases lacking any bacterial identification due to previous antimicrobial treatment for parameningeal foci. This raises some major problems about early diagnosis, validity and signification of lumbar punctures, and usefulness of starting treatment with large spectrum antibiotics.
在一项为期20年的调查(1960年至1980年)中,收集了146例曾患细菌性脑膜炎的各年龄段儿童,并进行了回顾性研究。在我们的系列研究中,我们可以证实文献中出现的突出的流行病学和临床特征。值得注意的是,由于先前针对脑膜旁病灶进行了抗菌治疗,很大比例的病例未能进行任何细菌鉴定。这就早期诊断、腰椎穿刺的有效性和意义以及开始使用广谱抗生素治疗的实用性提出了一些重大问题。