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Betaine: a promising novel anti-aging substance as an exercise mimetic.

作者信息

Liu Yonghui, Lin Jiang

机构信息

College of Basic Medicine, Guangxi University of Chinese Medicine, Nanning, China.

出版信息

Front Pharmacol. 2025 Aug 28;16:1672934. doi: 10.3389/fphar.2025.1672934. eCollection 2025.

DOI:10.3389/fphar.2025.1672934
PMID:40949146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12423099/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd6/12423099/1bd8d82f9202/fphar-16-1672934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd6/12423099/66a66cc207a7/fphar-16-1672934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd6/12423099/1bd8d82f9202/fphar-16-1672934-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd6/12423099/66a66cc207a7/fphar-16-1672934-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fd6/12423099/1bd8d82f9202/fphar-16-1672934-g002.jpg

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本文引用的文献

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Systematic profiling reveals betaine as an exercise mimetic for geroprotection.系统分析表明，甜菜碱是一种模拟运动的老年保护剂。
Cell. 2025 Jun 25. doi: 10.1016/j.cell.2025.06.001.
2
Molecular and Cellular Mechanisms of Immunosenescence: Modulation Through Interventions and Lifestyle Changes.免疫衰老的分子和细胞机制：通过干预措施和生活方式改变进行调节
Biology (Basel). 2024 Dec 27;14(1):17. doi: 10.3390/biology14010017.
3
Exercise and exerkines: Mechanisms and roles in anti-aging and disease prevention.运动与运动因子：抗衰老及疾病预防中的机制与作用
Exp Gerontol. 2025 Feb;200:112685. doi: 10.1016/j.exger.2025.112685. Epub 2025 Jan 16.
4
Ovarian aging in humans: potential strategies for extending reproductive lifespan.人类卵巢衰老：延长生殖寿命的潜在策略。
Geroscience. 2023 Aug;45(4):2121-2133. doi: 10.1007/s11357-023-00768-8. Epub 2023 Mar 13.
5
Clinical effect and biological mechanism of exercise for rheumatoid arthritis: A mini review.运动治疗类风湿关节炎的临床疗效及生物学机制：小型综述。
Front Immunol. 2023 Jan 6;13:1089621. doi: 10.3389/fimmu.2022.1089621. eCollection 2022.
6
Hallmarks of aging: An expanding universe.衰老的特征：一个不断扩大的领域。
Cell. 2023 Jan 19;186(2):243-278. doi: 10.1016/j.cell.2022.11.001. Epub 2023 Jan 3.
7
Exercise for Primary and Secondary Prevention of Cardiovascular Disease: JACC Focus Seminar 1/4.运动与心血管疾病的一级和二级预防：JACC 焦点研讨会 1/4。
J Am Coll Cardiol. 2022 Sep 13;80(11):1091-1106. doi: 10.1016/j.jacc.2022.07.004.
8
Invest in physical activity to protect and promote health: the 2020 WHO guidelines on physical activity and sedentary behaviour.投资于身体活动以保护和促进健康：2020 年世卫组织关于身体活动和 sedentary behaviour 的指南。
Int J Behav Nutr Phys Act. 2020 Nov 26;17(1):145. doi: 10.1186/s12966-020-01051-1.
9
Physical exercise in the prevention and treatment of Alzheimer's disease.体力活动在阿尔茨海默病的预防和治疗中的作用。
J Sport Health Sci. 2020 Sep;9(5):394-404. doi: 10.1016/j.jshs.2020.01.004. Epub 2020 Feb 4.
10
Diet and exercise in the prevention and treatment of type 2 diabetes mellitus.饮食和运动在 2 型糖尿病的预防和治疗中的作用。
Nat Rev Endocrinol. 2020 Oct;16(10):545-555. doi: 10.1038/s41574-020-0381-5. Epub 2020 Jul 20.