Wu Sheng, Zheng Ye, Mou Jiang-Wei, Zhang Yan-Jun, Zhu Ke-Xiang
The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China.
Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
World J Gastrointest Surg. 2025 Aug 27;17(8):108312. doi: 10.4240/wjgs.v17.i8.108312.
Pancreatic duct stones (PDS) pose substantial therapeutic challenges owing to their tendency to induce recurrent pain and discomfort mechanical irritation and ductal obstruction, resulting in a marked decline in patients' quality of life. The pathogenesis of pancreatic duct calculi remains incompletely understood due to its multifactorial and intricate nature. Advances in minimally invasive endoscopic interventions have broadened the available treatment modalities for PDS. This review summarizes current perspectives on the mechanisms driving stone formation alongside evolving therapeutic strategies.
胰管结石（PDS）因其易于引发反复疼痛和不适、机械刺激及导管阻塞，导致患者生活质量显著下降，从而带来了巨大的治疗挑战。由于胰管结石的发病机制具有多因素和复杂性，目前仍未完全明确。微创内镜干预技术的进展拓宽了胰管结石的可用治疗方式。本综述总结了目前关于结石形成机制的观点以及不断发展的治疗策略。
