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回顾性分析影响磁共振引导放疗中自由呼吸时呼吸运动幅度的患者因素。

Retrospective review of patient factors impacting free-breathing respiratory motion magnitude for MR-guided radiotherapy.

作者信息

Daly Mairead, Egan Holly, Choudhury Ananya, Radhakrishna Ganesh, Eccles Cynthia L

机构信息

Faculty of Biology, Medicine and Health, The University of Manchester, UK.

The Christie NHS Foundation Trust, Manchester, UK.

出版信息

Tech Innov Patient Support Radiat Oncol. 2025 Aug 28;35:100339. doi: 10.1016/j.tipsro.2025.100339. eCollection 2025 Sep.

Abstract

Patient factors may influence motion management strategy selection for abdominal stereotactic ablative radiotherapy (SABR). This retrospective evaluation investigated the impact of body mass index (BMI), sex, and cirrhosis in 16 patients imaged with cine-magnetic resonance imaging (MRI) on a 1.5 T magnetic resonance linear accelerator (MR Linac). Male patients, those with cirrhosis, and higher BMI tended to exhibit greater motion magnitude, although this was not statistically significant, suggesting that these patients should be prioritised for motion management strategies. Further investigation in larger cohorts is warranted to confirm these trends and guide personalised motion management in abdominal radiotherapy.

摘要

患者因素可能会影响腹部立体定向消融放疗(SABR)的运动管理策略选择。这项回顾性评估调查了16例在1.5T磁共振直线加速器(MR Linac)上进行电影磁共振成像(MRI)检查的患者的体重指数(BMI)、性别和肝硬化对运动的影响。男性患者、患有肝硬化的患者以及BMI较高的患者往往表现出更大的运动幅度,尽管这在统计学上并不显著,这表明这些患者应优先采用运动管理策略。有必要在更大的队列中进行进一步研究,以证实这些趋势并指导腹部放疗中的个性化运动管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ff/12423660/6b012bbb822b/gr1.jpg

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