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短期局部使用类固醇激素后进行粘连松解术治疗包皮粘连的疗效

Efficacy of Short Duration of Topical Steroids Followed by Adhesiolysis for Management of Preputial Adhesions.

作者信息

Bose Sumona

机构信息

Department of Paediatric Surgery, All India Institute of Medical Sciences, Kalyani, West Bengal, India.

出版信息

J Indian Assoc Pediatr Surg. 2025 Sep-Oct;30(5):622-629. doi: 10.4103/jiaps.jiaps_10_25. Epub 2025 Jul 25.

Abstract

AIMS

The primary objective was to evaluate the efficacy of a 2-week course of topical corticosteroids and outpatient adhesiolysis in managing preputial adhesions. Secondary objectives included assessing adhesion recurrence rates and monitoring adverse effects related to corticosteroid application and adhesiolysis.

MATERIALS AND METHODS

This prospective observational study was conducted at a tertiary care hospital. Boys presenting with symptoms such as inability to retract the prepuce, ballooning, penile swelling/smegma, urinary symptoms, or history of balanitis were enrolled. Preputial retractability was assessed using the KIKIROS scale. Symptomatic boys with lower KIKIROS grades underwent adhesiolysis during the first visit. Others were advised to apply topical steroids twice daily for 2 weeks, followed by adhesiolysis.

RESULTS

In the 0-<5 years group, the inability to retract prepuce with other symptoms (31%) and ballooning (26%) were common. In the 5-<10 years group, 43.8% had inability to retract the prepuce with associated conditions. In the 10-<17 years group, 64% had inability to retract the prepuce. Post-ointment KIKIROS grading was predominantly 3 in all age groups. After the fifth follow-up, 79.55% of boys who underwent adhesiolysis without ointment achieved KIKIROS 0, compared to 55.39% of those who used ointment.

CONCLUSION

Topical steroids are helpful, but adhesiolysis alone shows higher efficacy, especially for those with lower initial KIKIROS grades. Reassurance is appropriate for asymptomatic boys under five, while older boys often benefit from intervention. Post-procedure hygiene education and regular follow-up are crucial to minimize recurrence.

摘要

目的

主要目标是评估为期2周的局部皮质类固醇疗程及门诊粘连松解术治疗包皮粘连的疗效。次要目标包括评估粘连复发率以及监测与皮质类固醇应用和粘连松解术相关的不良反应。

材料与方法

这项前瞻性观察性研究在一家三级护理医院进行。纳入出现如包皮无法上翻、鼓包、阴茎肿胀/包皮垢、泌尿系统症状或龟头炎病史等症状的男孩。使用KIKIROS量表评估包皮可上翻性。KIKIROS评分较低的有症状男孩在首次就诊时接受粘连松解术。其他男孩被建议每天两次外用类固醇,持续2周,随后进行粘连松解术。

结果

在0至<5岁组中,包皮无法上翻伴其他症状(31%)和鼓包(26%)较为常见。在5至<10岁组中,43.8%的男孩包皮无法上翻并伴有相关情况。在10至<17岁组中,64%的男孩包皮无法上翻。所有年龄组在涂抹药膏后的KIKIROS分级主要为3级。在第五次随访后,未使用药膏而接受粘连松解术的男孩中有79.55%达到KIKIROS 0级,而使用药膏的男孩中这一比例为55.39%。

结论

局部类固醇有帮助,但单独的粘连松解术显示出更高的疗效,尤其是对于初始KIKIROS分级较低的患者。对于5岁以下无症状的男孩,给予安慰即可,而年龄较大的男孩通常从干预中获益。术后卫生教育和定期随访对于减少复发至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49fd/12425383/0b6231be3403/JIAPS-30-622-g001.jpg

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