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儿童漏斗胸的微创修复:来自单一机构的大型队列研究的见解

Minimally invasive repair of pectus excavatum in children: insights from a large cohort at a single institution.

作者信息

Park Hyung Joo, Rim Gongmin, Yoon Seung Keun

机构信息

Department of Pediatric Thoracic Surgery, Cleveland Clinic Children's Hospital, Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Department of Thoracic and Cardiovascular Surgery, Cha Bundang Hospital, College of Medicine, Cha University, Seongnam, South Korea.

出版信息

J Thorac Dis. 2025 Aug 31;17(8):5663-5679. doi: 10.21037/jtd-24-1199. Epub 2025 Aug 22.

Abstract

BACKGROUND

The outcomes and potential for recurrence following surgical correction of pectus excavatum (PE) in the pediatric population remain unresolved. We carried out non-delayed PE repair in all patients aged 5 years or older. This study aimed to verify the safety and effectiveness of pediatric PE repair, based on our 10-year research data, focusing on the incidence of recurrence and the advanced strategy of using the crane sternal pre-lifting and multiple pectus bars for anatomical chest wall remodeling.

METHODS

From January 2013 to July 2023, a cohort of 816 pediatric patients aged ≤10 years (range, 3-10 years) underwent PE repair using pectus bars to assess the outcomes of the procedure. Among these, we specifically focused on 173 patients who underwent surgery within the last 3 years (2020-2022), during which our approach shifted to the multiple bar technique for pediatric patients. This subset was divided into the single-bar (Group S, 87 patients) and multiple-bar (Group M, 86 patients) approaches for comparison. The analysis of outcomes included changes in the computed tomography severity index (Haller index), complication rates, length of hospital stay, and reoperation incidence, with a specific focus on recurrence.

RESULTS

The two groups had similar baseline characteristics, and there was no recurrence in either group in the recent 3-year analysis. In the single- and multiple-bar group comparisons, most Group M patients underwent repair with two pectus bars (2 bars: 84, 3 bars: 2, P=0.045). The length of stay showed no significant difference between the groups (Group S; 4.63 days Group M: 4.40 days, P=0.22). Among complications, there were no life-threatening complications. Similar rates of occurrence of pleural effusion (Group S, 2.3% Group M, 2.3%, P=0.96), pneumothorax (Group S, 2.3% Group M, 3.4%, P=0.75), and wound complications (Group S, 1.2% Group M, 0%, P=0.32) were observed in both groups. However, Group M showed less total intravenous rescue analgesic consumption (Group S, 16.5 mg Group M, 13.92 mg, P<0.01).

CONCLUSIONS

Our findings showed no significant increase in the risk of recurrence or major complications with the approach of non-delayed PE repair for all patients aged 5 years and older. Our transition from a single-bar to a multiple-bar repair approach has been crucial for achieving a thorough anatomical remodeling of the entire chest wall. This strategic shift has proven to be a safe and effective surgical method, applicable even to pediatric PE patients.

摘要

背景

小儿漏斗胸(PE)手术矫正后的预后及复发可能性仍不明确。我们对所有5岁及以上患者进行了非延迟性PE修复。本研究旨在基于我们10年的研究数据,验证小儿PE修复的安全性和有效性,重点关注复发率以及采用胸骨预提升和多根鸡胸矫正棒进行胸廓解剖重塑的先进策略。

方法

2013年1月至2023年7月,一组816例年龄≤10岁(范围3 - 10岁)的小儿患者接受了使用鸡胸矫正棒的PE修复,以评估该手术的效果。其中,我们特别关注了最近3年(2020 - 2022年)接受手术的173例患者,在此期间我们对小儿患者的手术方法转向了多根矫正棒技术。该亚组分为单根矫正棒组(S组,87例患者)和多根矫正棒组(M组,86例患者)进行比较。结果分析包括计算机断层扫描严重指数(哈勒指数)的变化、并发症发生率、住院时间和再次手术发生率,特别关注复发情况。

结果

两组基线特征相似,在最近3年的分析中两组均无复发。在单根矫正棒组和多根矫正棒组的比较中,M组大多数患者使用两根鸡胸矫正棒进行修复(2根:84例,3根:2例,P = 0.045)。两组住院时间无显著差异(S组;4.63天 M组:4.40天,P = 0.22)。在并发症方面,无危及生命的并发症。两组胸腔积液发生率相似(S组,2.3% M组,2.3%,P = 0.96)、气胸发生率相似(S组,2.3% M组,3.4%,P = 0.75)以及伤口并发症发生率相似(S组,1.2% M组,0%,P = 0.32)。然而,M组的总静脉急救镇痛药物消耗量较少(S组,16.5 mg M组,13.92 mg,P < 0.01)。

结论

我们的研究结果表明,对于所有5岁及以上患者,非延迟性PE修复方法的复发风险或主要并发症没有显著增加。我们从单根矫正棒修复方法向多根矫正棒修复方法的转变对于实现整个胸廓的彻底解剖重塑至关重要。这一策略转变已被证明是一种安全有效的手术方法,甚至适用于小儿PE患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e46/12433051/480b3c46b748/jtd-17-08-5663-f1.jpg

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