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机器人辅助胸腔镜手术(RATS):挪威一家医院连续200例肺叶切除术的学习曲线和结果

Robot-assisted thoracic surgery (RATS): learning curve and outcomes for 200 consecutive pulmonary lobectomies in a Norwegian hospital.

作者信息

Maksimovic Nina, Neumann Kirill, Aamodt Henrik, Eggum Rune, Reier-Nilsen Frode, Wesche Jarlis, Stavem Knut

机构信息

Faculty of Medicine, University of Oslo, Campus Ahus, Lørenskog, Norway.

Department of Vascular and Thoracic Surgery, Akershus University Hospital, Lørenskog, Norway.

出版信息

J Thorac Dis. 2025 Aug 31;17(8):5936-5950. doi: 10.21037/jtd-2024-2240. Epub 2025 Aug 27.

Abstract

BACKGROUND

When starting with new surgical procedures, a gradual improvement in skills and results is expected. Pulmonary resection for early-stage non-small cell lung cancer (NSCLC) has advanced with technology, making robot-assisted thoracic surgery (RATS) an increasingly preferred method. At Akershus University Hospital (Ahus), exploring the learning curve associated with RATS offered valuable insights for optimizing surgical efficiency and improving patient outcomes. This study analyzes key operational variables and outcomes to highlight the skill acquisition process at a leading Norwegian healthcare center, aiming to describe the learning curve involved in transitioning from video-assisted thoracic surgery (VATS) to RATS for lung cancer lobectomies.

METHODS

This study was a retrospective analysis of the first 200 consecutive pulmonary lobectomies and bi-lobectomies with RATS in Norwegian University Hospital. We used cumulative sum (CUSUM) and risk-adjusted CUSUM (RA-CUSUM) analyses to evaluate operative times and perioperative complications.

RESULTS

The 200 patients had a median age of 70 (25-75 percentile, 62-75) years; 109 (55%) were female, 159 (80%) had preoperative stage 0-IB, and 34 (17%) stage IIA-IIB. Of the procedures, 196 were lobectomies and 4 bi-lobectomies. Median operating time was 160 (25-75 percentile, 120-195) minutes. Complications (Clavien-Dindo grade ≥2) were observed in 25.5% of cases. The conversion rate to thoracotomy was 1.5% and re-operation rate 3.0%. CUSUM analysis indicated a bi-phasic learning curve for operative times, with ongoing improvements observed after the 117 procedure. The RA-CUSUM analysis showed a steady decline in perioperative complications after the 94 procedure.

CONCLUSIONS

The findings suggest that the transition from VATS to RATS as a standard surgical approach for pulmonary lobectomies was associated with an acceptable development of proficiency, procedure duration, and complication rates over time. Hence, implementation of the new RATS program was feasible and effective.

摘要

背景

在开展新的外科手术时,技能和手术效果有望逐步提高。早期非小细胞肺癌(NSCLC)的肺切除术随着技术的发展而进步,使得机器人辅助胸外科手术(RATS)越来越成为首选方法。在阿克什胡斯大学医院(Ahus),探索与RATS相关的学习曲线为优化手术效率和改善患者预后提供了宝贵的见解。本研究分析关键手术变量和结果,以突出挪威一家领先的医疗中心的技能获取过程,旨在描述在肺癌肺叶切除术中从电视辅助胸腔镜手术(VATS)过渡到RATS所涉及的学习曲线。

方法

本研究是对挪威大学医院连续进行的首例200例RATS肺叶切除术和双肺叶切除术的回顾性分析。我们使用累积和(CUSUM)分析及风险调整累积和(RA-CUSUM)分析来评估手术时间和围手术期并发症。

结果

200例患者的中位年龄为70(25 - 75百分位数,62 - 75)岁;109例(55%)为女性,159例(80%)术前处于0 - IB期,34例(17%)处于IIA - IIB期。在这些手术中,196例为肺叶切除术,4例为双肺叶切除术。中位手术时间为160(25 - 75百分位数,120 - 195)分钟。25.5%的病例观察到并发症(Clavien-Dindo分级≥2级)。开胸手术转化率为1.5%,再次手术率为3.0%。CUSUM分析表明手术时间呈双相学习曲线,在第117例手术后持续改善。RA-CUSUM分析显示在第94例手术后围手术期并发症稳步下降。

结论

研究结果表明,作为肺叶切除术的标准手术方法,从VATS过渡到RATS随着时间的推移在熟练程度、手术时长和并发症发生率方面有可接受的进展。因此,新的RATS项目的实施是可行且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d51/12433073/de6b2fd0b656/jtd-17-08-5936-f1.jpg

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