Sulthana Huma, Jan Asif, Verma Amogh, Sah Ranjana, Mehta Rachana, Ullah Aftab, Rahim Abdur, Alqudimat Mohammad R, Ullah Asmat
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciences, Bangalore, India.
Saidu Group of Teaching Hospitals, Saidu Sharif, Pakistan.
Front Public Health. 2025 Aug 29;13:1662234. doi: 10.3389/fpubh.2025.1662234. eCollection 2025.
The increasing popularity of electronic cigarettes (e-cigarettes) has introduced new public health challenges and concerns. While promoted as safer alternatives to conventional tobacco and as tools for quitting smoking, e-cigarettes have raised alarm about possible long-term health consequences. This systematic review and meta-analysis sought to evaluate the association between electronic cigarette consumption and sleep disturbances.
We performed comprehensive searches in EMBASE, Web of Science, and PubMed up to September 18, 2024, to locate studies examining the link between e-cigarette use and sleep duration, sleep disorders, and insomnia. A meta-analysis was conducted to calculate pooled odds ratios (ORs). The quality of the studies was evaluated using the Newcastle-Ottawa Scale. Meta-analysis was performed using R software (Version 4.3).
A total of 14 cross-sectional studies were included from 554 unique records screened. E-cigarette users exhibited a notably elevated risk of having shorter sleep duration compared to non-users, with a pooled odds ratio of 1.38 (95% CI: 1.24-1.55). Several studies reported that e-cigarette users also had higher odds of sleep disturbances, such as insomnia and reliance on sleep medications. Among adolescents, e-cigarette use was associated with a 33 to 61% increased risk of inadequate sleep.
E-cigarette use may be associated with sleep disturbances, including shorter sleep duration and increased sleep difficulties. Future long term longitudinal studies are warranted for better evidence.
电子烟越来越受欢迎，带来了新的公共卫生挑战和问题。虽然电子烟被宣传为比传统烟草更安全的替代品以及戒烟工具，但人们对其可能产生的长期健康后果感到担忧。本系统评价和荟萃分析旨在评估电子烟消费与睡眠障碍之间的关联。
截至2024年9月18日，我们在EMBASE、科学网和PubMed中进行了全面检索，以查找研究电子烟使用与睡眠时间、睡眠障碍和失眠之间联系的研究。进行荟萃分析以计算合并优势比（OR）。使用纽卡斯尔-渥太华量表评估研究质量。使用R软件（版本4.3）进行荟萃分析。
从筛选的554条独特记录中纳入了14项横断面研究。与非使用者相比，电子烟使用者睡眠持续时间较短的风险显著升高，合并优势比为1.38（95%CI：1.24-1.55）。几项研究报告称，电子烟使用者出现睡眠障碍的几率也更高，如失眠和对助眠药物的依赖。在青少年中，使用电子烟与睡眠不足风险增加33%至61%相关。
使用电子烟可能与睡眠障碍有关，包括睡眠时间缩短和睡眠困难增加。未来需要进行长期纵向研究以获得更好的证据。
