School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Research and Enterprise, University of Cyberjaya, Persiaran Bestari, Cyber 11, Cyberjaya, Selangor, 63000, Malaysia.
BMC Public Health. 2024 Nov 18;24(1):3200. doi: 10.1186/s12889-024-20746-9.
As e-cigarettes gain popularity as potential tobacco cessation aids, concerns arise about their dual use with traditional cigarettes, especially among pregnant women, potentially subjecting both women and fetuses to heightened risks. This systematic review and meta-analysis aimed to determine the overall prevalence of dual use of tobacco smoking and e-cigarette use in pregnant women.
A literature search was conducted across databases including PubMed, Embase, Web of Science, and Cochrane on October 20, 2023. The included studies reported the number of pregnant women and the count of those who were dual users. Quality assessment was undertaken using the JBI tool. The pooled prevalence of dual use was determined via a random-effects model. All statistical analyses were executed using R software, version 4.3.
CRD42023486020.
Eighteen studies were analyzed, encompassing 5,983,363 pregnant women. The meta-analysis indicated an overall prevalence of 4.6% (95% CI: 2.0-10.3) for dual users with significant heterogeneity (I = 100%). Subgroup analysis based on the country showed a prevalence of 4.9% (95% CI: 2.0 to 11.6) for USA and 8.1% (95% CI: 0.00 to 1.00) for UK. Meta-regression revealed reduction of prevalence of dual use from 2019 to 2023. A potential publication bias was indicated by the LFK index and the Doi plot.
The dual consumption of e-cigarettes and traditional tobacco in pregnant women is a significant health concern, with a notable prevalence. Given the established risks of tobacco smoking during pregnancy and the uncertainties surrounding e-cigarettes, more comprehensive research and public health interventions are urgently needed to address this issue.
随着电子烟作为潜在的戒烟辅助工具越来越受欢迎，人们对其与传统香烟同时使用的情况产生了担忧，尤其是在孕妇中，这可能使妇女和胎儿面临更高的风险。本系统评价和荟萃分析旨在确定孕妇同时使用烟草吸烟和电子烟的总体流行率。
我们于 2023 年 10 月 20 日在 PubMed、Embase、Web of Science 和 Cochrane 等数据库中进行了文献检索。纳入的研究报告了孕妇人数和双重使用者人数。使用 JBI 工具进行质量评估。通过随机效应模型确定双重使用的汇总流行率。所有统计分析均使用 R 软件，版本 4.3 执行。
分析了 18 项研究，共纳入 5983363 名孕妇。荟萃分析表明，双重使用者的总体流行率为 4.6%（95%CI：2.0-10.3），存在显著异质性（I=100%）。基于国家的亚组分析显示，美国的流行率为 4.9%（95%CI：2.0 至 11.6），英国为 8.1%（95%CI：0.00 至 1.00）。Meta 回归显示，从 2019 年到 2023 年，双重使用的流行率有所下降。LFK 指数和 Doi 图表明存在潜在的发表偏倚。
孕妇同时使用电子烟和传统烟草是一个重大的健康问题，其流行率相当高。鉴于怀孕期间吸烟的既定风险以及围绕电子烟的不确定性，迫切需要进行更全面的研究和公共卫生干预，以解决这一问题。
