Boicelli C A, Baratta B, Giuliani A M
Physiol Chem Phys Med NMR. 1985;17(3):247-54.
The proton longitudinal relaxation time of regenerating rat liver has been found to increase during the first 24 hours after hepatectomy and to drop back to normal in the following hours. The decreased relaxation rate may be related to the increase of the water mobility due to the expansion of the intercellular spaces during the massive proliferation of the first day, or to the increased cell hydration which is known to occur during active cell proliferation. Equations have been derived for the proliferation process, and the competing inhibition process, active from the 24th hour, which can quantitatively account for the proton relaxation behaviour.
已发现再生大鼠肝脏的质子纵向弛豫时间在肝切除后的头24小时内增加，并在随后的数小时内恢复正常。弛豫率降低可能与第一天大量增殖期间细胞间隙扩大导致的水流动性增加有关，或者与活跃细胞增殖期间已知发生的细胞水合作用增加有关。已推导了增殖过程以及从第24小时开始起作用的竞争性抑制过程的方程，这些方程可以定量解释质子弛豫行为。
