Kuroda Kenji, Hamamoto Koetsu, Kawamura Kazuki, Masunaga Ayako, Kobayashi Hiroaki, Ito Keiichi
Department of Urology, National Defense Medical College, Tokorozawa, Saitama, Japan.
J Midlife Health. 2025 Jul-Sep;16(3):301-308. doi: 10.4103/jmh.jmh_106_25. Epub 2025 Sep 5.
Laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery (TVM) have been shown to effectively treat pelvic organ prolapse (POP). However, their effects on urinary incontinence (UI) remain unknown, particularly when conducted on patient groups with similar backgrounds. We here aimed to compare the postoperative UI-related symptoms between patient groups without preoperative statistical differences.
We retrospectively evaluated 243 patients with POP who underwent LSC or TVM at our hospital. Ninety-six patients were treated by LSC, whereas 147 were treated by TVM. After using nearest-neighbor propensity score matching, we compared the postoperative UI-related symptoms between the matched 67 LSC-treated patients and 67 TVM-treated patients.
Following propensity score matching, the matched LSC and TVM groups did not demonstrate significant differences in terms of the explanatory factors. In both matched groups, the overactive bladder symptom score (OABSS) and International Consultation on Incontinence Questionnaire Short-Form (ICIQ-SF) score were significantly decreased at 3-12 months postoperatively compared with preoperative variables. The 60-min pad weight test revealed a significant decrease in the LSC and TVM groups at 12 months postoperatively. When comparing the results at 1 year postoperatively with preoperative values, the matched LSC and TVM groups demonstrated no significant differences in changes of the 60-min pad weight, OABSS, and ICIQ-SF score.
TVM appears to be a more favorable option for managing all types of POP than LSC, considering its shorter operative time and lower complication rate, as shown using nearest-neighbor propensity score matching analysis.
腹腔镜骶骨阴道固定术(LSC)和经阴道网状物手术(TVM)已被证明可有效治疗盆腔器官脱垂(POP)。然而,它们对尿失禁(UI)的影响仍不明确,尤其是在对背景相似的患者群体进行手术时。我们旨在比较术前无统计学差异的患者群体术后与尿失禁相关的症状。
我们回顾性评估了我院243例接受LSC或TVM治疗的盆腔器官脱垂患者。96例患者接受LSC治疗,147例接受TVM治疗。在使用最近邻倾向评分匹配后,我们比较了67例接受LSC治疗的匹配患者和67例接受TVM治疗的匹配患者术后与尿失禁相关的症状。
倾向评分匹配后,匹配的LSC组和TVM组在解释因素方面无显著差异。在两个匹配组中,与术前变量相比,术后3至12个月膀胱过度活动症症状评分(OABSS)和国际尿失禁咨询问卷简表(ICIQ-SF)评分均显著降低。60分钟垫重量试验显示,LSC组和TVM组术后12个月均显著下降。将术后1年的结果与术前值进行比较时,匹配的LSC组和TVM组在60分钟垫重量、OABSS和ICIQ-SF评分的变化方面无显著差异。
使用最近邻倾向评分匹配分析显示,考虑到手术时间较短和并发症发生率较低,TVM似乎是治疗所有类型盆腔器官脱垂比LSC更有利的选择。