Bohard Louis, Brumpt Eléonore, Tissot Noémie, Lacoste Marie, Chapuis Olivia, Felix Sophie, Knapp Jenny, Hartmann-Gouvenot Carole, Jeffredo Yannick, Grenouillet Frederic, Montange Damien, Bellanger Anne-Pauline, Chirouze Catherine, Bresson-Hadni Solange
Infectious Diseases Department, Jean Minjoz University Hospital Besançon, Besançon, France.
UMR CNRS Chrono environment laboratory, Marie et Louis Pasteur University, Besançon, France.
PLoS Negl Trop Dis. 2025 Sep 15;19(9):e0013511. doi: 10.1371/journal.pntd.0013511. eCollection 2025 Sep.
Alveolar and cystic echinococcoses (AE and CE) are parasitic zoonoses, mainly affecting the liver. Primary extrahepatic localizations remain rare and are difficult to diagnose. We report two cases of primary subcutaneous echinococcosis and the largest literature review on the subject. The first case is an alveolar echinococcosis located in the forehead region and the second a cystic echinococcosis in the abdominal wall. To our knowledge, a primary AE location in the face has never been described before. Pre-surgical diagnosis was not made in these two cases. However, it is essential to apply specific measures, depending on the type of echinococcosis (AE or CE), to prevent parasitic dissemination and recurrence. In view of the cases presented here, prolonged albendazole can be a second-line alternative to a surgical strategy. Echinococcosis should be kept in mind for differential diagnosis of soft tissue lesions in any part of the body.
肺泡型和囊型棘球蚴病（AE和CE）是寄生虫性人畜共患病，主要累及肝脏。原发性肝外定位仍然罕见且难以诊断。我们报告了两例原发性皮下棘球蚴病病例以及关于该主题的最大规模文献综述。第一例是位于前额区域的肺泡型棘球蚴病，第二例是腹壁的囊型棘球蚴病。据我们所知，此前从未有过面部原发性AE定位的描述。这两例病例术前均未做出诊断。然而，根据棘球蚴病的类型（AE或CE）采取特定措施以防止寄生虫传播和复发至关重要。鉴于此处呈现的病例，延长阿苯达唑治疗可作为手术策略的二线选择。对于身体任何部位软组织病变的鉴别诊断都应考虑到棘球蚴病。
