Koppen Tim, Barth Thomas F E, Eichhorn Klaus W, Gabrielpillai Jennis, Kader Ralph, Bootz Friedrich, Send Thorsten
Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.
Institute of Pathology, University of Ulm, Albert-Einstein Allee 11, 89081 Ulm, Germany.
Pathogens. 2021 Apr 3;10(4):426. doi: 10.3390/pathogens10040426.
(1) Background: (AE) is restricted to the northern hemisphere with high endemic regions in Central Europe, North and Central Asia as well as Western China. The larval stage of causes AE with tumor-like growth. Humans are accidental hosts. This report is on the first case of AE becoming clinically manifested in the parotic gland. (2) Case presentation: A 52-year-old male patient presented with progressive and painful swelling of the right parotid gland persisting for one year. We performed a partial parotidectomy. The histological examination and immunohistological staining revealed larval stage of . (3) Conclusion: is known to infect animals and humans coincidentally, and leads to AE. It is one of the most life-threatening zoonoses in Europe. It typically manifests in the liver (50-77%), with further spreading to other organs being a rare phenomenon. Echinococcosis should be considered in the differential diagnosis of lesions of the parotid gland in endemic areas, but AE has not been described so far in the parotid gland as the sole manifestation and, therefore, impedes the correct diagnosis. A complete resection should be the aim, however, preservation of the facial nerve and adjuvant albendazole therapy is mandatory.
(1) 背景：泡型包虫病（AE）局限于北半球，在中欧、北亚和中亚以及中国西部为高流行区。其幼虫阶段可引发具有肿瘤样生长的泡型包虫病。人类是偶然宿主。本报告介绍了首例在腮腺出现临床表现的泡型包虫病病例。(2) 病例介绍：一名52岁男性患者，右侧腮腺进行性疼痛肿胀持续一年。我们实施了部分腮腺切除术。组织学检查和免疫组织化学染色显示为泡型包虫幼虫阶段。(3) 结论：已知泡型包虫可同时感染动物和人类，并导致泡型包虫病。它是欧洲最具生命威胁的人畜共患病之一。其通常在肝脏表现出来（50 - 77%），扩散到其他器官的情况较为罕见。在流行地区，腮腺病变的鉴别诊断中应考虑棘球蚴病，但迄今为止，泡型包虫病尚未被描述为仅在腮腺出现的表现，因此会妨碍正确诊断。然而，应以完整切除为目标，同时必须保留面神经并辅助使用阿苯达唑进行治疗。
