Tao Wenjuan, Zhang Li, Li Yong, Bai Yinling, Chen Ting, Wei Wei, Lin Xiaojun, Chen Mao, Wen Jin
Institute of Hospital Management, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
BMJ Open. 2025 Sep 15;15(9):e094691. doi: 10.1136/bmjopen-2024-094691.
To examine whether longer holidays are associated with worse quality of care for patients with ST-segment elevation myocardial infarction (STEMI) compared with weekday admissions and to evaluate the impact of holiday duration on both process indicators and mortality outcomes.
Retrospective observational study.
Nationwide study across 3278 hospitals in China participating in the China Cardiovascular Association Database-Chest Pain Centre Registry.
A total of 616 382 STEMI episodes from 1 January 2016 to 31 December 2021 were included.
Primary outcome was in-hospital mortality. Secondary outcomes included process indicators: initial ECG acquisition within 10 min, thrombolytic treatment within 30 min and door-to-balloon time within 90 min. Admissions were categorised as weekday (reference), weekend, short-term holiday (3-5 days) or long-term holiday (7-10 days).
Long-term holidays were associated with a 10% increased risk of in-hospital mortality (OR=1.10, 95% CI: 1.02 to 1.18, p<0.05), with a 17% increased risk during the Spring Festival (OR=1.17, 95% CI: 1.09 to 1.25, p<0.01). Weekends showed a 5% increased mortality risk (OR=1.05, 95% CI: 1.02 to 1.09, p<0.01). Initial ECG acquisition within 10 min improved during long-term holidays (OR=1.15, 95% CI: 1.10 to 1.21, p<0.001). However, short-term holidays were associated with worse performance for thrombolytic treatment within 30 min (OR=0.83, 95% CI: 0.76 to 0.91, p<0.01) and door-to-balloon time within 90 min (OR=0.83, 95% CI: 0.80 to 0.87, p<0.01). Primary-secondary hospitals showed lower odds of timely percutaneous coronary intervention during long-term holidays (OR=0.83, 95% CI: 0.75 to 0.92, p<0.001), while tertiary hospitals were more affected during short-term holidays (OR=0.82, 95% CI: 0.79 to 0.86, p<0.001).
Longer holidays, particularly the Spring Festival, are associated with slightly worse outcomes for patients with STEMI in China. While initial assessments may be expedited during holidays, delays occur in providing definitive treatment. These findings highlight the need for targeted strategies to maintain high-quality STEMI care during extended holiday periods.
探讨与工作日入院相比,更长的假期是否与ST段抬高型心肌梗死(STEMI)患者的护理质量较差相关,并评估假期时长对过程指标和死亡率结局的影响。
回顾性观察研究。
在中国心血管病协会数据库-胸痛中心注册研究中对全国3278家医院进行的研究。
纳入了2016年1月1日至2021年12月31日期间共616382例STEMI发作病例。
主要结局是院内死亡率。次要结局包括过程指标:10分钟内进行初始心电图检查、30分钟内进行溶栓治疗以及90分钟内的门球时间。入院被分类为工作日(对照)、周末、短期假期(3-5天)或长期假期(7-10天)。
长期假期与院内死亡风险增加10%相关(OR=1.10,95%CI:1.02至1.18,p<0.05),春节期间风险增加17%(OR=1.17,95%CI:1.09至1.25,p<0.01)。周末显示死亡风险增加5%(OR=1.05,95%CI:1.02至1.09,p<0.01)。长期假期期间10分钟内进行初始心电图检查的情况有所改善(OR=1.15,95%CI:1.10至1.21,p<0.001)。然而,短期假期与30分钟内溶栓治疗表现较差相关(OR=0.83,95%CI:0.76至0.91,p<0.01)以及90分钟内门球时间较差相关(OR=0.83,95%CI:0.80至0.87,p<0.01)。一级和二级医院在长期假期期间及时进行经皮冠状动脉介入治疗的几率较低(OR=0.83,95%CI:0.75至0.92,p<0.001),而三级医院在短期假期期间受影响更大(OR=0.82,95%CI:0.79至0.86,p<0.001)。
更长的假期,尤其是春节,与中国STEMI患者稍差的结局相关。虽然假期期间初始评估可能会加快,但在提供确定性治疗方面会出现延迟。这些发现凸显了在长假期间制定针对性策略以维持高质量STEMI护理的必要性。