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“非工作时间”效应及内镜检查环境对食管食物嵌塞患者治疗结果的影响

The "After Hours" Effect and Role of Endoscopy Setting on Outcomes in Patients with Esophageal Food Impaction.

作者信息

Wadhavkar Neha, Roussel Breton, Monteiro Joao Filipe, Bains Kanwal, Bhowmick Kuntal, Mohamed Mouhand, Kalligeros Markos, Fine Sean

机构信息

Department of Medicine, The Warren Alpert Medical School of Brown University, 593 Eddy St, Providence, RI, 02903, USA.

University Gastroenterology, Providence, RI, USA.

出版信息

Dig Dis Sci. 2025 Sep 15. doi: 10.1007/s10620-025-09389-x.

Abstract

BACKGROUND AND AIMS

Esophageal food impaction (EFI) resulting in obstruction is a gastrointestinal emergency requiring disimpaction by upper endoscopy. Current guidelines recommend emergent intervention within 24 h to reduce risk of complications. However, limited data exist regarding specific factors affecting practice patterns, including timing and setting of endoscopic intervention for EFI.

METHODS

We conducted a retrospective review of 684 patients who presented with EFI to the emergency department (ED) at three hospitals from 2015-2021. 447 patients met inclusion criteria. We compared hospitalization rates, ED triage-to-endoscopy time, sedation type, endoscopy setting [ED/intensive care unit (ICU), operating room (OR), or endoscopy unit (EU)], and complications for "business hours" (between 8AM and 5PM) and "after hours" procedures (weekends or before 8AM/after 5PM).

RESULTS

Among 509 EFI cases, 67.2% were performed "after hours," and 56.2% occurred in the EU. "After hours" endoscopies were over fourfold more likely to involve moderate sedation (OR 4.35 [1.64-11.54]). Mean ED triage-to-endoscopy time was significantly longer for "business hours" cases (11.3 ± 21.2 h versus 5.4 ± 10.3 h, adjusted p-value = 0.0002). Patients undergoing endoscopy "after hours" were 74% less likely to be hospitalized (0.26 [0.13-0.55]). Although not statistically significant, "after hours" cases had lower complication rates (2.3 versus 4.8%) and in-hospital mortality (0.0% vs 1.2%) compared to "business hours" (p-value ≤ 0.1367 and ≤ 0.1072, respectively).

CONCLUSIONS

We found that "after hours" endoscopic disimpactions for EFI did not have increased hospitalizations or increased complications relative to "business hours," contrary to current literature. Our findings underscore the safety, efficacy, and feasibility of "after hours" endoscopic intervention for EFI, which may help shape resource allocation and hospital protocols to improve patient outcomes in the future.

摘要

背景与目的

导致食管梗阻的食管食物嵌塞(EFI)是一种胃肠道急症,需要通过上消化道内镜进行解除嵌塞。当前指南建议在24小时内进行紧急干预,以降低并发症风险。然而,关于影响实践模式的具体因素,包括EFI内镜干预的时机和地点,相关数据有限。

方法

我们对2015年至2021年期间在三家医院急诊科就诊的684例EFI患者进行了回顾性研究。447例患者符合纳入标准。我们比较了“工作时间”(上午8点至下午5点)和“非工作时间”(周末或上午8点前/下午5点后)的住院率、急诊科分诊至内镜检查的时间、镇静类型、内镜检查地点[急诊科/重症监护病房(ICU)、手术室(OR)或内镜室(EU)]以及并发症情况。

结果

在509例EFI病例中,67.2%在“非工作时间”进行,56.2%在内镜室进行。“非工作时间”的内镜检查使用中度镇静的可能性高出四倍多(比值比4.35 [1.64 - 11.54])。“工作时间”病例的平均急诊科分诊至内镜检查时间显著更长(11.3 ± 21.2小时对5.4 ± 10.3小时,调整后p值 = 0.0002)。“非工作时间”接受内镜检查的患者住院可能性降低74%(0.26 [0.13 - 0.55])。尽管无统计学意义,但与“工作时间”相比,“非工作时间”病例的并发症发生率较低(2.3%对4.8%),院内死亡率也较低(0.0%对1.2%)(p值分别≤0.1367和≤0.1072)。

结论

我们发现,与“工作时间”相比,EFI的“非工作时间”内镜解除嵌塞并未增加住院率或并发症发生率,这与当前文献报道相反。我们的研究结果强调了EFI“非工作时间”内镜干预的安全性、有效性和可行性,这可能有助于未来合理分配资源和制定医院方案,以改善患者预后。

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