Sun Gang, Zeng Jia-Qi, Wu Jun-Ling, Wang Shu-Fang, Peng Li-Hua, Yan Bin, Pan Fei, Li Yi, Zhou Guan-Zhou, Chen Xiao-Dong, Wang Zi-Kai, Wang Xiang-Dong, Lian Wan-Yuan, Yang Yun-Sheng
Department of Gastroenterology and Hepatology, the First Medical Center, Chinese PLA General Hospital, Beijing, 100853, China.
Department of Medical College of Chinese PLA, Beijing, 100853, China.
Mil Med Res. 2025 Sep 15;12(1):57. doi: 10.1186/s40779-025-00644-w.
At present, no commercially available endoscopic system is specifically designed for use in the battlefield, disaster relief, or unique environments with biosafety concerns. Therefore, this limitation stems from challenges such as limited portability, reliance on stable power, complex disinfection processes, and the risk of incomplete sterilization. To address these challenges, we developed a novel portable endoscopic system and evaluated its safety and effectiveness in both routine settings and specialized scenarios, including the global pandemic caused by a novel coronavirus, which represents an environment with biosafety concerns.
After sample size calculation, 30 patients underwent esophagogastroduodenoscopy (EGD) or colonoscopy using the YunSendo (the experimental group) and Olympus systems (the control group) in a randomized order. Operation time, image quality, operational performance, lesion detection, and safety were assessed. Ten emergency patients with suspected upper gastrointestinal bleeding received bedside treatment using the YunSendo system during the global pandemic caused by a novel coronavirus. Clinical outcomes in emergency endoscopic treatment were assessed.
No significant differences were observed between the YunSendo and Olympus groups in terms of image quality, lesion detection, and overall procedural performance. YunSendo facilitated biopsy and colonic polyp removal; no adverse endoscopy events were reported. YunSendo successfully executed diagnostic and therapeutic procedures in emergencies, with no observed mortality at 1, 7, or 30 d, no rebleeding at 1 or 30 d, and no cross-infection rates.
The performance of the YunSendo portable endoscopic system was comparable to the Olympus system in terms of key metrics, demonstrating its utility in urgent scenarios. This novel system is particularly promising for medical rescue and military missions and for addressing battlefield and biosafety concerns.
目前，尚无专门为战场、救灾或存在生物安全问题的特殊环境设计的商用内镜系统。因此，这种局限性源于便携性有限、依赖稳定电源、消毒过程复杂以及灭菌不完全的风险等挑战。为应对这些挑战，我们开发了一种新型便携式内镜系统，并在常规环境和特殊场景中评估了其安全性和有效性，包括由新型冠状病毒引起的全球大流行，这代表了一个存在生物安全问题的环境。
在计算样本量后，30例患者随机先后使用云森多（实验组）和奥林巴斯系统（对照组）进行食管胃十二指肠镜检查（EGD）或结肠镜检查。评估操作时间、图像质量、操作性能、病变检测和安全性。在新型冠状病毒引起的全球大流行期间，10例疑似上消化道出血的急诊患者使用云森多系统接受了床边治疗。评估急诊内镜治疗的临床结果。
云森多组和奥林巴斯组在图像质量、病变检测和总体操作性能方面未观察到显著差异。云森多便于活检和结肠息肉切除；未报告不良内镜事件。云森多在紧急情况下成功执行了诊断和治疗程序，在1天、7天或30天时未观察到死亡病例，在1天或30天时无再出血情况，且无交叉感染率。
云森多便携式内镜系统在关键指标方面的性能与奥林巴斯系统相当，证明了其在紧急情况下的实用性。这种新型系统在医疗救援和军事任务以及解决战场和生物安全问题方面特别有前景。
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